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Penehyclidine Hydrochloride: A Promising Antimuscarinic Agent for PONV Prophylaxis in Diverse Surgical Procedures.
J Perianesth Nurs
January 2025
Department of Otorhinolaryngology, Al Mouwasat University Hospital, Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic; Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic.
Purpose: The purpose of this meta-analysis is to measure the effectiveness of penehyclidine hydrochloride hydrate (PHC)-an antimuscarinic drug-in preventing postoperative nausea and vomiting (PONV) for different surgeries.
Design: Meta-analysis.
Methods: According to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, we conducted an online literature search using PubMed, Web of Science, Scopus, and Embase databases.
Neurological management of ischemic stroke in sickle cell disease- a case report with an updated review of the literature.
Neurol Sci
December 2024
Department of Neuroscience, Imaging, and Clinical Science, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Background: In children and adults with sickle-cell disease (SCD), acute ischemic stroke (AIS) associated with a vaso-occlusive crisis is a leading cause of physical and cognitive disability and death. However, neurological guidelines for acute management of AIS fail to directly address this issue. We here report a case of a man with severe cerebrovascular complications and illustrate the current evidence on the management of SCD-related AIS.
View Article and Find Full Text PDFSpontaneous Tumor Lysis Syndrome in a Thoracic Burkitt Lymphoma: A Case Report.
Cureus
November 2024
Hematology, Centro Hospitalar de Setúbal, Hospital de São Bernardo, Setúbal, PRT.
Burkitt lymphoma has a high proliferation rate and a significant risk of tumor lysis syndrome. Risk stratification and early identification are imperative since it is an oncological emergency. We report the case of a 20-year-old woman, without relevant past medical history, admitted to the Emergency Department with a three-week history of fatigue, chest discomfort, productive cough, night sweats, myalgia, odynophagia, and holocranial headache.
View Article and Find Full Text PDFSpontaneous Intracranial Hypotension and Dural Ectasia in Marfan Syndrome: An Illustrative Case Successfully Treated with Steroid Therapy and Literature Review.
Brain Sci
November 2024
Institute of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University, 00168 Roma, Italy.
Article Synopsis
- Spontaneous intracranial hypotension (SIH) is a rare condition often misdiagnosed, particularly in patients with connective tissue disorders like Marfan Syndrome, which can lead to structural weaknesses in the spinal dural membrane and increased risk of CSF leaks.
- A 52-year-old woman with genetically confirmed Marfan Syndrome presented with severe headaches and diplopia; imaging revealed complications such as dural ectasia and subdural hematoma, which were effectively managed with bed rest and corticosteroids.
- A review of 25 studies on SIH treatment in patients with Marfan Syndrome indicated high success rates for symptoms improvement, particularly with epidural blood patches and conservative treatments.
A Case of Dengue Fever With Multiserotype IgG Positivity.
Cureus
October 2024
Internal Medicine, Howard University Hospital, Washington, DC, USA.
Dengue fever is a rapidly spreading mosquito-borne viral disease, increasingly endemic in tropical and subtropical regions. This case report details the clinical presentation of a 52-year-old male who developed severe symptoms shortly after returning from a two-week trip to El Salvador, an area known for dengue endemicity. The patient presented with a five-day history of high-grade fever, malaise, diarrhea, dizziness, and intermittent blurry vision, accompanied by chills, dry cough, headaches, and generalized pain.
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