Down's syndrome is the most common autosomal chromosomal abnormality in humans and is associated with a number of well known clinical findings. Atlantoaxial instability is a less recognized, yet potentially significant, manifestation of Down's that has gained importance because of the widespread participation of Down's syndrome individuals in athletic events. Early recognition and appropriate management of patients with atlantoaxial instability can significantly reduce the morbidity and mortality associated with this condition and guide patients and their parents toward continued safe participation in athletics.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Diagnosis, Classifications and Treatment of Os Odontoideum: WFNS Spine Committee Recommendations.
Spine (Phila Pa 1976)
January 2025
Department of Neurosurgery, Lilavati Hospital and Research Center, Bandra, Mumbai, India.
Study Design: A systematic literature review and consensus using Delphi method.
Objective: The aim was to formulate consensus recommendations regarding the natural history, diagnosis, classification and optimal treatment of Os Odontoideum with global applicability.
Summary Of Background: Os odontoideum (OO) is a rare anomaly of the cranio-vertebral junction (CVJ).
Superior biomechanical stability of pedicle screws compared to lateral mass screws: recommendations for bicortical positioning and enhancing bone contact in geriatric C1 vertebrae.
J Orthop Surg Res
January 2025
Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg- Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Background: In atlantoaxial instabilities, posterior C1/C2 fusion using lateral mass screws (LMS) or pedicle screws (PS) in a mono- or bicortical position in the atlas is a typical treatment. The bone microstructure and positioning of the screw trajectories appear to be of significant relevance for stability.
Purpose: The aim of this study was a comparative analysis of the mechanical durability of screw fixation concerning microstructural characteristics of the trajectories of LMS and PS in mono- and bicortical position.
Non-instrumented management of traumatic atlanto-axial rotatory subluxation: surgical technique.
J Spine Surg
December 2024
Department of Neurosurgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Atlantoaxial rotatory subluxation (AARS) in the adult population is primarily trauma-induced. Conservative and surgical treatments have both been used successfully in treating AARS. In cases where AARS cannot be reduced by conservative measures, open reduction and fusion is the conventional treatment approach.
View Article and Find Full Text PDFCerebellar infarction due to atlantoaxial subluxation in spondyloepimetaphyseal dysplasia-joint laxity type 1 case.
Clin Dysmorphol
December 2024
Department of Pediatric Genetics.
Introduction: Spondyloepimetaphyseal dysplasia with joint laxity type 1 (SEMD-JL1) is an extremely rare skeletal dysplasia belonging to a group of disorders called linkeropathies. It is characterized by skeletal and connective tissue abnormalities. Biallelic variants in genes encoding enzymes that synthesize the tetrasaccharide linker region of glycosaminoglycans lead to linkeropathies, which exhibit clinical and phenotypic features that overlap with each other.
View Article and Find Full Text PDFFactors Associated With the Absence of Cervical Spine Instability in Rheumatoid Arthritis: A >10-Year Prospective Multicenter Cohort Study.
Neurospine
December 2024
Department of Orthopedic Surgery, Kobe Rosai Hospital, Kobe, Japan.
Objective: To identify factors associated with the absence of cervical spine instability in patients with rheumatoid arthritis (RA).
Methods: Cervical spine instability was defined as the presence of at least one of the following: atlantoaxial subluxation, vertical subluxation of the axis, or subaxial subluxation. In 2001-2002, 634 enrolled outpatients with "classical" or "definite" RA underwent a radiographic cervical spine checkup.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!