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http://dx.doi.org/10.1097/00000441-195507000-00005 | DOI Listing |
Fitoterapia
July 2024
The Bartholin Institute, Rigshospitalet Department, 3733, Copenhagen Biocenter, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark. Electronic address:
The introduction of glucagon-like peptide 1 (GLP-1)-based therapies has greatly improved the management of type 2 diabetes (T2D), as they ensure good blood glucose control and promote weight loss. Ingestion of standardized herbal remedies that promote the same endogenous metabolic processes affected by the GLP-1-based treatments could provide cheaper alternatives in low- and middle-income countries, where there is currently an increase in the incidence of T2D. The focus in this study was to determine quality control parameters and the prime factors for the Rauvolfia-Citrus tea (RC-tea), as used in Nigerian traditional medicine to treat T2D.
View Article and Find Full Text PDFChin Herb Med
April 2024
Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Objective: To isolate bioactive compounds from the endophytic fungus isolated from , and investigate their pharmacological activities.
Methods: The chemical constituents were isolated and purified by combining with ODS column chromatography, silica gel column chromatography and by performing semipreparative HPLC. Their structures were established on the basis of 1D NMR (H-NMR and C-NMR) and 2D NMR (H-H COSY, HSQC, HMBC and NOESY), as well as HRESIMS and comparison with literature data.
Environ Sci Pollut Res Int
January 2024
Department of Chemistry, Environment Protection Laboratory, Central University of Jharkhand, Ranchi, 835205, India.
The application of green synthesized nanocomposites for the prevention of environmental pollution is increasing nowadays. Here, a green composite has been synthesized by embedding MnO on Rauvolfia tetraphylla leaves using its leaf extract hereinafter termed as MnO@RTL, and demonstrated for crystal violet (CV) dye removal from simulated and real wastewater. The surface properties of the material were determined by scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX), Fourier transform infrared spectra (FTIR), X-ray diffraction (XRD), and Brunauer-Emmet-Teller (BET) surface area, pH, and zeta potential.
View Article and Find Full Text PDFCommun Biol
November 2023
Biomolécules et Biotechnologies Végétales, EA2106, Université de Tours, 37200, Tours, France.
Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized metabolites mainly produced in Gentianales to cope with environmental challenges. Due to their pharmacological properties, the biosynthetic modalities of several MIA types have been elucidated but not that of the yohimbanes. Here, we combine metabolomics, proteomics, transcriptomics and genome sequencing of Rauvolfia tetraphylla with machine learning to discover the unexpected multiple actors of this natural product synthesis.
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