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Ann Hepatol
June 2018
Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, and Health Sciences Center, University of Guadalajara, Mexico.
Occult hepatitis B infection (OBI) is the presence of hepatitis B virus (HBV) DNA in the liver and/or serum (< 200 IU/mL) in HBsAgnegative patients with or without serologic markers of previous viral exposure. The clinical significance of OBI is of concern in posttransfusional hepatitis B infection, hepatitis B reactivation, chronic liver disease and hepatocellular carcinoma (HCC). The diagnosis of OBI relays on the use of highly sensitive and specific laboratory techniques.
View Article and Find Full Text PDFEur J Haematol
June 2013
Ospedale Regionale per le Microcitemie, ASL8, Cagliari, Italy.
Background: Transfusion-acquired hepatitis C virus (HCV) remains an important problem among patients with thalassemia. In this study, we evaluated the natural history of post-transfusional hepatitis C in thalassemia major, paying special attention to spontaneous viral clearance, to factors influencing the chronicity rate and fibrosis progression.
Design And Methods: A prospective study to evaluate the incidence and etiology of transfusion-related hepatitis was started in 1980.
BioDrugs
October 1999
Istituto di Malattie Infettive, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, Naples, Italy.
Hepatitis C virus (HCV) affects millions of individuals worldwide. In most cases, HCV infection progresses to chronic liver disease and, subsequently, to liver cirrhosis and hepatocellular carcinoma. HCV is transmitted by the parenteral route, for example by transfusion of blood or blood products, injection during drug abuse, etc.
View Article and Find Full Text PDFMed Clin (Barc)
June 2006
Servicio de Hepatología, Institut de Malalties Digestives i Metabòliques, Hospital Clínic, Barcelona, España.
Spain has a medium endemicity of hepatitic C infection among central Europe countries and Italy. Prevalence of anti-HCV varies among regions and it ranges from 1.6 to 2.
View Article and Find Full Text PDFRev Gastroenterol Mex
September 2005
Servicio de Gastroenterología, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), México.
Objective: To determine the epidemiological situation of Chronic Hepatitis C (CHC) in our country.
Background Data: Chronic Hepatitis C affects 170 million people worldwide, and about 0.7% of Mexican population.
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