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Eating "rubbish"? Exploring the herbal secrets of "Laji-He," a traditional herbal rice snack from southern China.

J Ethnobiol Ethnomed

January 2025

Lushan Botanical Garden, Jiangxi Province and Chinese Academy of Sciences, Lushan, 332900, China.

Background: Laji-He is a traditional rice-based snack from the Beibu Gulf region in southern China. In the Beibu Gulf region, "Laji-He" (literally "garbage He") signifies the removal of toxins from the body, making it a truly "green" food. Laji-He holds essential cultural and medicinal value, incorporating various medicinal plants into its preparation.

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This article details the development of a next-word prediction model utilizing federated learning and introduces a mechanism for detecting backdoor attacks. Federated learning enables multiple devices to collaboratively train a shared model while retaining data locally. However, this decentralized approach is susceptible to manipulation by malicious actors who control a subset of participating devices, thereby biasing the model's outputs on specific topics, such as a presidential election.

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NME7 maintains primary cilium assembly, ciliary microtubule stability, and Hedgehog signaling.

Life Sci Alliance

April 2025

https://ror.org/0040axw97 Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China

NME7 (nucleoside diphosphate kinase 7), a lesser studied member of the non-metastatic expressed (NME) family, has been reported as a potential subunit of the γ-tubulin ring complex (γTuRC). However, its role in the cilium assembly and function remains unclear. Our research demonstrated that NME7 is located at the centrosome, including at the spindle poles during metaphase and at the basal bodies during cilium assembly.

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Single-cell RNA flow cytometry to assess intratumoral production of cytokines/chemokines.

Methods Cell Biol

January 2025

Inflammatory Cell Dynamics Section, Laboratory of Integrative Cancer Immunology (LICI), Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, MD, United States. Electronic address:

The tumor microenvironment (TME) consists of complex interactions between cellular and extracellular components, among which the immune system is known to play an integral role in disease progression and response to therapy. Cytokines and chemokines are cell signaling proteins used by immune cells to communicate with each other as well as with other cell types in the body. These proteins control systemic and local immune responses and levels of cytokines/chemokines in the TME have been associated with tumor outcomes.

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Identifying Key Weather Factors Influencing Human Salmonellosis: A Conditional Incidence Analysis in England, Wales, and the Netherlands.

J Infect

January 2025

School of Veterinary Medicine, University of Surrey, Daphne Jackson Rd, Guildford GU2 7AL, United Kingdom; The Surrey Institute for People-Centred Artificial Intelligence, Stag Hill University Campus, Guildford GU2 7XH, United Kingdom; Institute for Sustainability, University of Surrey, Guildford, United Kingdom; University of Exeter, Exeter, United Kingdom.

Objectives: This study aimed to improve the understanding of seasonal incidence pattern observed in salmonellosis by identifying the most influential weather factors, characterizing the nature of this association, and assessing whether it is geographically restricted or generalizable to other locations.

Methods: A novel statistical model was employed to estimate the incidence of salmonellosis conditional to various combinations of three simultaneous weather factors from 14 available. The analysis utilised daily salmonellosis cases reported from 2000 to 2016 along with detailed spatial and temporal weather data from England and Wales, and the Netherlands.

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