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Meningitis due to Gemella sp. in a patient with severe ENT conditions: case report and review of the literature.
Ann Clin Microbiol Antimicrob
December 2024
Laboratoire de Microbiologie, Centre Hospitalier de Valenciennes, Valenciennes, F-59300, France.
In June 2022, a 73-year-old man with a history of laryngeal and esophageal carcinoma was admitted to the emergency unit with sudden fever, confusion, and general condition deterioration. Initial assessments showed a fever of 38.5 °C, elevated C-reactive protein (CRP) at 209 mg/L, and a neutrophil count of 10.
View Article and Find Full Text PDFZinc Ameliorates High Pi and Ca-Mediated Osteogenic Differentiation of Mesenchymal Stem Cells.
Nutrients
November 2024
MTA-DE Lendület Vascular Pathophysiology Research Group, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Zinc is the second most abundant trace element in the human body, stored mainly in the bones. Zinc is required for bone growth and homeostasis and is also a crucial cofactor for numerous proteins that play key roles in maintaining microstructural integrity and bone remodeling. Bone marrow-derived mesenchymal stem cells (BMSCs) are multipotent progenitors found in the bone marrow stroma and can differentiate along multiple lineage pathways.
View Article and Find Full Text PDFSuccessful Triple Flap Procedure for Thumb Reconstruction in Severe Hand Crush Injury.
Am J Case Rep
December 2024
Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Sleman, Yogyakarta, Indonesia.
BACKGROUND The thumb is crucial for the aesthetic and functional aspects of the upper extremity. A crushed thumb injury can be particularly challenging, especially for individuals with high demands. Currently, there is no consensus on the best approach for treating a crushed thumb.
View Article and Find Full Text PDFMultifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bone defects .
Theranostics
December 2024
Department of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan University, 168 Donghu Street, Wuchang District, Wuhan 430071 Hubei, China.
Article Synopsis
- Factor-free biomaterial scaffolds are crucial for bone repair, but diabetes complicates healing due to issues like oxidative stress and infection.
- A new multifunctional platform called GAD/MC, using copper-containing TiCT MXene nanosheets and hydrogels, aims to improve therapy for bone defects in diabetic patients.
- This platform features enhanced mechanical properties, self-healing abilities, and can release bioactive copper in response to environmental changes, promoting antibacterial effects and reducing inflammation to support healing.
Chronic brucellosis with sacroiliitis: A case report.
Clin Case Rep
November 2024
Maharajgunj Medical Campus Institute of Medicine, Tribhuvan University Kathmandu Nepal.
Article Synopsis
- Brucellosis is a rare but challenging disease to diagnose, especially when it involves the joints, and should be considered in patients with prolonged fever and joint pain.
- A case study of a 41-year-old goat farmer highlighted her symptoms of low back and joint pain lasting four months, leading to a diagnosis confirmed by serological tests.
- Early detection and treatment, including NSAIDs and antibiotics, resulted in complete symptom relief within four weeks, emphasizing the importance of detailed history and physical exams in diagnosing atypical cases.
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