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The largest single-center report on intravenous leiomyomatosis and development of a classification to guide surgical management.
J Vasc Surg Venous Lymphat Disord
January 2025
Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Article Synopsis
- - The study evaluates intravenous leiomyomatosis (IVL), a rare tumor, over a 20-year period, offering insights into its characteristics and prognosis through a comprehensive classification system for surgical management.
- - Researchers reviewed data from 216 patients who underwent IVL resection, finding that recurrence rates differed significantly between complete and incomplete resection groups, with specific factors influencing outcomes.
- - This report, the largest of its kind, enhances understanding of IVL clinical features and long-term results while providing a useful classification tool for assessing lesion severity and guiding surgical decisions.
A case of diffuse cavernous hemangioma involving the uterus and vagina.
Asian J Surg
September 2024
Department of Radiology, The Second Hospital of Dalian Medical University, 467 Zhong Shan Road, Dalian, 116023, PR China.
Large placental chorioangioma with maternal and perinatal morbidity.
Eur J Obstet Gynecol Reprod Biol
September 2024
Department of Pathology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Article Synopsis
- Placental chorioangioma is a benign tumor typically without complications, but this case involves a large tumor leading to serious maternal and fetal issues during labor.
- A 38-year-old woman with a history of miscarriage experienced preterm labor at 33 weeks due to a 12x10 cm placental tumor and underwent an emergency caesarean delivery after signs of fetal distress.
- Following delivery, the mother and baby faced complications, including postpartum hemorrhage and neonatal anemia, highlighting the need for a multidisciplinary approach to manage such cases effectively.
Implications of the Hippo Pathway Dysregulation in Uterine Leiomyosarcoma.
Anticancer Res
August 2024
Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Article Synopsis
- - Uterine leiomyosarcomas (uLMS) are common tumors in the female reproductive system, and their genetics are complex, involving the Hippo pathway, which plays a role in various cancer types through its effectors YAP1 and TAZ.
- - A study analyzed tissue samples from 32 uLMS patients, looking at the Hippo pathway's role and its relation to clinical factors such as age, stage, and treatment outcomes.
- - The results showed that 62.5% of patients had disrupted Hippo signaling, and this was linked to improved overall survival rates, suggesting the pathway's significance in uLMS development and prognosis.
Unexpected placental tumor: A case report.
Int J Surg Case Rep
August 2024
Tunis El Manar University, Faculty of Medicine of Tunis, 1007 Tunis, Tunisia; Charles Nicolle Hospital, Department of Pathology, Tunis, Tunisia.
Introduction And Importance: Placental non-trophoblastic tumors (PNTT) are uncommon, consisting mainly of chorangiomas, placental teratomas (PT) and haemangiomas. PT are exceedingly rare, with less than 40 cases reported in the literature. We, herein, present a case of mature PT arising within the membranes, and we aim to discuss the clinico-pathological characteristics of this rare entity.
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