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Skin cancer risk in over 200.000 patients with haematologic malignancies in 30 years; a nationwide population-based study in the Netherlands.
Br J Dermatol
January 2025
Department of Dermatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.
Background: Patients with haematologic malignancies are at increased risk of developing skin cancer and often experience worse skin cancer-related outcomes. However, there is a lack of nationwide, population-based data with long-term follow-up on the incidence and risks of different skin cancer types across all haematologic malignancies.
Objectives: To assess population-based risk estimates for cutaneous squamous cell carcinoma (CSCC), malignant melanoma (MM), Merkel cell carcinoma (MCC), and basal cell carcinoma (BCC) among patients with haematologic malignancies, stratified by skin cancer type and haematologic malignancy subgroup.
Biological, Biomechanical, and Histopathological Evaluation of Polyetherketoneketone Bioactive Composite as Implant Material.
J Biomed Mater Res B Appl Biomater
February 2025
Department of Prosthodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
While polyetherketoneketone is a high-performance thermoplastic polymer, its hydrophobicity and inertness limit bone adhesion. This study aimed to evaluate a novel PEKK/CaSiO/TeO nanocomposite, comparing it to PEKK/15 wt.% CaSiO and PEKK groups.
View Article and Find Full Text PDFInjection of hyaluronic acid versus platelet rich plasma for treatment of vulvovaginal atrophy in post-menopausal females.
Arch Dermatol Res
January 2025
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Female sexual dysfunction is highly prevalent among postmenopausal females approaching 50%, with vulvovaginal atrophy (VVA) being a cardinal sign. For decades, hormone replacement therapy was the only solution to relieve symptoms associated with this atrophy. However, it was limited by its serious side effects, raising the need for new treatment strategies.
View Article and Find Full Text PDFPatient-derived xenograft models of gastrointestinal stromal tumors: a ready-to-use platform for translational research.
Dis Model Mech
January 2025
Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven Cancer Institute, Leuven, Belgium.
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal malignancy of the gastrointestinal tract. Most GIST harbor mutations in oncogenes, such as KIT, and are treated with tyrosine kinase inhibitors (TKI), such as imatinib. Most tumors develop secondary mutations inducing drug resistance against the available TKI, which requires novel therapies.
View Article and Find Full Text PDF[Breast Cancer in Male Patients of the Aconcagua Valley During the Period 2013-2018].
Rev Med Chil
September 2024
Escuela de Medicina, Facultad de Medicina, Universidad de Valparaíso, San Felipe, Chile.
Unlabelled: Breast cancer in men is a rare disease, accounting for around 1% of all cancers in males. Diagnosis often occurs in advanced stages due to low awareness of this disease in males.
Aim: To evaluate the clinical, epidemiological, and histopathological characteristics of breast cancer in men in the Aconcagua Valley and its relationship with patient survival.
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