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Modality-, feature-, and strategy-dependent organization of low-level working memory.
J Vis
January 2025
Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Previous research has shown that, when multiple similar items are maintained in working memory, recall precision declines. Less is known about how heterogeneous sets of items across different features within and between modalities impact recall precision. In two experiments, we investigated modality (Experiment 1, n = 79) and feature-specific (Experiment 2, n = 154) load effects on working memory performance.
View Article and Find Full Text PDFChrysanthemum extract mitigates high-fat diet-induced inflammation, intestinal barrier damage and gut microbiota disorder.
Food Funct
January 2025
Institute of Food Nutrition and Quality Safety, College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
An effective intervention for obesity without side effects is needed. Chrysanthemum may be the preferred choice due to its influence in the improvement of glycolipid metabolism. This study assessed the efficacy of chrysanthemum and its flavonoids in mitigating high-fat diet (HFD) induced obesity, focusing on the integrity of the intestinal barrier, inflammation, and gut microbiota.
View Article and Find Full Text PDFStudy on Influence of Microwave Electric Field Direction on Evaporation Based on Molecular Dynamics.
J Phys Chem A
January 2025
College of Electronics and Information Engineering, Sichuan University, Chengdu 610065, China.
Microwave-assisted evaporation technology is widely used today, but its molecular mechanism is not fully understood. To investigate the molecular mechanism of the influence of microwave electric field direction on water evaporation, this paper designed experiments to measure the microwave energy required to evaporate each gram of water with electric field directions parallel and perpendicular to the water surface. The temperature rise curve of the water is controlled to be consistent in both cases, and the temperature distribution of the water is made uniform by stirring.
View Article and Find Full Text PDFResearch on detection methods of related substances and degradation products of the antitumor drug selpercatinib.
Front Chem
January 2025
Department of Oncology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Background: Selpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer. The presence of process-related and degradation impurities in its active pharmaceutical ingredient (API) can significantly affect its safety and effectiveness. However, research on detecting these impurities is limited.
View Article and Find Full Text PDFSilent Hearing Loss in Kidney Transplant Patients Receiving Tacrolimus: A Fact or a Myth?
Indian J Nephrol
June 2024
Mansoura Nephrology and Dialysis Unit, Department of Internal Medicine, Mansoura, Egypt.
Background: It has been claimed that tacrolimus may have harmful effects on the auditory system, where it has been linked to ototoxicity and sensorineural hearing loss (SNHL). We evaluated silent SNHL in kidney transplant recipients (KTRs) receiving tacrolimus and the different factors affecting it compared to healthy controls.
Materials And Methods: In this case control study, hearing functions were studied in 42 KTRs receiving tacrolimus as maintenance immunosuppressive therapy for more than 3 months in comparison to 27 age- and gender-matched healthy subjects using tympanometry, pure-tone audiometry (PTA), extended high frequency audiometry (EHFA), and transient evoked oto-acoustic emissions (TEOAEs).
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