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We studied modifying potentialities of high temperatures in treatment regimens with adjuvant endolymphatic chemo- and interferontherapy of malignant melanoma of the skin. We had previously obtained enough evidence for expediency of adjuvant endolymphatic therapy of primary-localized melanoblastoma of the skin. Added to the preventive treatment regimens were sessions of local magnetothermia.

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The indexes of the disease remission dynamics proved to be les favourable in patients with lymphogenic metastases revealed while the first visit to oncologist (stage T1-4N1M0) in comparison with those, in whom the metastases in regional lymph nodes have appeared after the primarily restricted cutaneous melanoma T1-4N1M0 excision. The survival indexes of the patients were similar.

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The results of treatment of 1128 patients with the body and extremities skin melanoma were analyzed. The increase of five-year survival index in patients with the tumor of T1-4 N0M0 stage by 11.4% was promoted by the postoperative adjuvant endolymphatic chemotherapy application.

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[Generalized melanoblastoma of the lower urinary tract].

Rozhl Chir

September 1994

Urologické oddĕlení FN Motol.

The primary metastatic melanoblastoma presented with macroscopic haematuria as a first sign is described. So far it is our first experience with such a type of tumor in lower urinary tract in ageing man. The references in literature are scarce on this subject.

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