Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson's model.
BMC Neurosci
January 2025
Department of Operative Dentistry and Periodontology, University Hospital Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by protein aggregates mostly consisting of misfolded alpha-synuclein (αSyn). Progressive degeneration of midbrain dopaminergic neurons (mDANs) and nigrostriatal projections results in severe motor symptoms. While the preferential loss of mDANs has not been fully understood yet, the cell type-specific vulnerability has been linked to a unique intracellular milieu, influenced by dopamine metabolism, high demand for mitochondrial activity, and increased level of oxidative stress (OS).
View Article and Find Full Text PDFObjectives: Primary Aldosteronism (PA) is a common but under-recognised cause of secondary hypertension. Early diagnosis with targeted medical and/or surgical intervention is important to prevent irreversible end-organ damage. An Endocrine Society Clinical Practice Guideline was used to define audit standards against which to assess current United Kingdom (UK) laboratory practice.
View Article and Find Full Text PDFInvestigation on luminescence characteristics of Dy-Tb co-doped phospho-tellurite glasses for tunable green/ white LED applications.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Physics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, West Bengal, India.
Dy/Tb co-doped glasses have drawn profound attention for their potential in solid state lighting due to their unique luminescence properties. This research highlights the effect of compositional variation on structural and optical characteristics of Dy/Tb co-doped phospho-tellurite glasses through a comprehensive analysis involving X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and photoluminescence (PL) studies. XRD and FTIR spectroscopy are conducted to characterize the glass matrix and confirm its structural integrity.
View Article and Find Full Text PDFIntroduction: Loss of skin integrity due to a wound or disease can lead to severe disability or even life threat. The highly expressed microRNAs in the skin are of great significance for skin development. The investigation purposed to explore the effect and mechanism of miR-211 on inflammation, oxidative stress and migration in keratinocytes.
View Article and Find Full Text PDFSuper-Resolved Mapping of Electrochemical Reactivity in Single 3D Catalysts.
Nano Lett
January 2025
Institute of Nanochemistry and Nanobiology, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, P.R. China.
Crystals with three-dimensional (3D) stereoscopic structures, characterized by diverse shapes, crystallographic planes, and morphologies, represent a significant advancement in catalysis. Differentiating and quantifying the catalytic activity of specific surface facets and sites at the single-particle level is essential for understanding and predicting catalytic performance. This study employs super-resolution radial fluctuations electrogenerated chemiluminescence microscopy (SRRF-ECLM) to achieve high-resolution mapping of electrocatalytic activity on individual 3D CuO crystals, including cubic, octahedral, and truncated octahedral structures.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!