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Comparison of end tidal CO levels between automated head up and conventional cardiopulmonary resuscitation: A pre-post intervention trial.
Resuscitation
November 2024
Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000, Grenoble, France; Clinical Epidemiology Unit, University Hospital of Grenoble Alpes, Grenoble, France.
Article Synopsis
- The study investigated the effects of a new CPR technique called AHUP-CPR, which combines head/thorax elevation, active compression-decompression, and an impedance threshold device, compared to traditional CPR in out-of-hospital cardiac arrest patients.
- It was conducted in France from October 2019 to October 2022, involving 122 patients, and aimed to measure the peak end tidal carbon dioxide (ETCO) values as a marker for cardiac output and organ perfusion during CPR.
- Results showed that AHUP-CPR significantly increased the mean peak ETCO values (from 30.3 mmHg to 40.7 mmHg), indicating better circulation, but there was no significant difference in the rates of
Effectiveness of combinations of active compression-decompression cardiopulmonary resuscitation, impedance threshold devices and head-up cardiopulmonary resuscitation in adult out-of-hospital cardiac arrest: A systematic review.
Resusc Plus
December 2024
Hampshire and Isle of Wight Air Ambulance, United Kingdom.
Objective: This review summarises the current evidence base for combinations of neuroprotective CPR adjuncts (active compression-decompression chest compressions, impedance threshold devices, and head-up positioning) during out-of-hospital cardiac arrest.
Methods: A systematic search (PROSPERO registration CRD42023432302) was performed in English on MEDLINE, EMBASE, and the Cochrane Library in August 2023, and repeated in February 2024. All randomised and observational studies (not abstracts) reporting on any combination of the aforementioned CPR adjuncts were included.
Active decompression during automated head-up cardiopulmonary resuscitation.
Resuscitation
September 2024
Department of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA. Electronic address:
Background: The combination of active compression-decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) and controlled head-up positioning (AHUP-CPR) is associated with improved outcomes compared with conventional CPR (C-CPR). This study focused on the role of active decompression (AD) during AHUP-CPR.
Methods: Farm pigs (n = 10, ∼40 kg) were anesthetized, intubated and ventilated.
Head up CPR is based upon the laws of physics.
Resuscitation
May 2024
Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN, USA; Department of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.
The association of regional cerebral oximetry and neurologically intact survival in a porcine model of cardiac arrest.
Resusc Plus
March 2024
Department of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.
Background: The objective of this study was to determine if regional cerebral oximetry (rSO2) assessed during CPR would be predictive of survival with favorable neurological function in a prolonged model of porcine cardiac arrest. This study also examined the relative predictive value of rSO2 and end-tidal carbon dioxide (ETCO2), separately and together.
Methods: This study is a post-hoc analysis of data from a previously published study that compared conventional CPR (C-CPR) and automated head-up positioning CPR (AHUP-CPR).
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