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Symmetrical peripheral gangrene caused by urosepsis: Case reports and literature review.
Medicine (Baltimore)
October 2024
Department of Critical Care Medicine, Anqing Municipal Hospital, Anqing City, Anhui Provinces, China.
Rationale: Symmetrical peripheral gangrene (SPG) is a serious and rare complication in patients with urosepsis, characterized by distal limb symmetry impairment.
Patient Concerns: In this study, 3 cases of SPG caused by urosepsis were reported, and the Chinese and English literature on SPG caused by urosepsis was reviewed. The demographic, clinicopathological, treatment, and follow-up data of the patients were summarized and analyzed.
Is the phoenix sign phenomenon due to vasodilation? A double-blinded, randomized controlled trial comparing motor function recovery after diagnostic common fibular nerve block with lidocaine and papaverine.
BMC Musculoskelet Disord
October 2024
NE Wyoming Wound Care Clinic, Sheridan, WY, USA.
Article Synopsis
- Focal entrapment of the common fibular nerve (CFN) is a common issue in the lower body that can be hard to diagnose, with a temporary strengthening response known as the "Phoenix sign" sometimes observed after lidocaine blocks.
- A study involving 20 patients tested the effects of two vasodilating agents, lidocaine and papaverine, on improving muscle strength in the anterior compartment by measuring the extensor hallucis longus (EHL) muscle before and after treatment.
- Results showed that both agents produced significant improvements in muscle strength without notable differences between them, suggesting the Phoenix Effect is likely due to improved local blood circulation.
Effects of Papaverine on Experimentally Induced Myringosclerosis.
J Craniofac Surg
October 2024
Department of Medical Pathology, İzmir Faculty of Medicine, University of Health Sciences Turkey, İzmir, Türkiye.
Article Synopsis
- The study investigates how papaverine affects myringosclerosis (MS) in rats, focusing on its impact on hearing issues caused by the condition.
- Twenty Wistar albino rats were divided into four groups to test different treatments, including myringotomy, saline application, and both systemic and topical papaverine.
- Results indicated that papaverine increased the severity of MS, possibly due to its vasodilating effects that lead to higher levels of oxygen-derived free radicals, warranting further evaluation of its implications on MS.
Novel endophytic fungal species Pithoascus kurdistanensis producing morphine compounds.
Sci Rep
September 2024
Institut de Biologie Intégrative et des Systèmes, Université Laval Québec, Québec, Canada.
Papaver genus, commonly known as popies, is a valuable source of alkaloids used in medicine, including papaverine, morphine, codeine, and thebaine. We isolated six endophytic fungal isolates producing morphinan alkaloids from four Papaver species growing in Kurdistan Province, Iran. To do this, a 1:1 mixture of methanol and chloroform was used to extract fungal cultures.
View Article and Find Full Text PDFKey Clinical Message: Topical papaverine is an effective vasodilator that can be used for dilating small veins to accept venous couplers for thumb replantation. This technique corrects size mismatches for successful venous anastomosis and minimizes postoperative complications.
Abstract: Thumb replantation is a complex microsurgical procedure used to restore function and appearance after amputation.
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