Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1365-2885.1992.tb01009.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Failure of doramectin and ivermectin in preventing Cochliomyia hominivorax myiasis in a subtropical region: A pharmacokinetic-pharmacodynamic study.
Vet Parasitol
December 2024
Laboratorio de Farmacología, Centro de Investigación Veterinaria de Tandil (CIVETAN), UNCPBA-CICPBA-CONICET, Campus Universitario, Tandil, Buenos Aires, Argentina.
The aim of this work is to present a case study where the failure of IVM 3.15 % and DRM 1 % to prevent natural infestations of C. hominivorax larvae in Argentina is investigated based on field efficacy tests and a pharmacokinetic and pharmacodynamic analysis.
View Article and Find Full Text PDFPharmacometric Analysis to Describe Pharmacokinetics and Exposure-Efficacy Response of Ivermectin in Adolescents Infected with Trichuris trichiura.
J Clin Pharmacol
November 2024
Certara, Radnor, PA, USA.
The efficacy of the combination therapy of albendazole and ivermectin against Trichuris trichiura infection is higher in Tanzania than in Côte d'Ivoire. This study therefore aimed to investigate the difference between the population pharmacokinetics (PK) at these study sites and to determine if an exposure-response analysis could explain the low efficacy of the combination therapy in Côte d'Ivoire. Twenty-four participants (aged 12-19 years) receiving single doses of ivermectin (200 µg/kg) and albendazole (400 mg) were included in the population PK modeling.
View Article and Find Full Text PDFPenetration Enhancer-Free Mixed Micelles for Improving Eprinomectin Transdermal c Efficiency in Animal Parasitic Infections Therapy.
Int J Nanomedicine
November 2024
College of Animal Medicine, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, People's Republic of China.
Introduction: Eprinomectin offers promise against parasitic infections. This study develops Eprinomectin (EPR) mixed micelles for transdermal delivery, aiming to enhance efficacy and convenience against endoparasites and ectoparasites. Physicochemical characterization and pharmacokinetic studies were conducted to assess its potential as an effective treatment for parasitic infections.
View Article and Find Full Text PDFThe effect of breed on ivermectin residues in the edible tissues of cattle and the estimated withdrawal period.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
January 2025
Research Centre for Veterinary Toxicology (CEPTOX) - Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, Pirassununga, SP, Brazil.
This study analyzed the residue depletion kinetics of ivermectin (IVM) in Nelore and crossbred (Nelore x Angus) cattle aiming to compare the profiles between the breeds and evaluate the residue levels at the injection site. IVM 1%, at a dose of 0.2 mg/kg, was administered the subcutaneous route, and tissue samples were collected on different days post administration for analysis by LC-MS/MS.
View Article and Find Full Text PDFTranscriptome reanalysis and gene expression of 13 detoxification genes for avermectin and pyridaben resistance in Panonychus citri.
Sci Rep
October 2024
Central Laboratory of the First Affiliated Hospital, WeiFang People's Hospital, Shandong Second Medical University, Weifang, 261000, China.
Citrus red mites (P. citri) are key pests affecting citrus production worldwide due to pesticide resistance. The resistance mechanisms of ten pesticides are known, but a comprehensive study using transcriptome data is missing.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!