Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection.
NIHR Open Res
January 2025
Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, England, L69 7BE, UK.
Background: PROTECT ( Platform Randomised evaluation of clinical Outcomes using novel TEChnologies to optimise antimicrobial Therapy) has brought together a team of researchers to design a platform trial to rapidly evaluate and adopt into care multiple diagnostic technologies, bringing immediate benefit to patients. Rapid diagnostic tests will be used to identify patients at risk of deterioration from severe infection, before they become critically unwell. The platform will assess their comparative clinical effectiveness and cost-effectiveness relative to current standard of care.
View Article and Find Full Text PDFBerberrubine protects against cisplatin-induced ototoxicity by promoting folate biosynthesis.
Front Pharmacol
January 2025
Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Objective: This research investigated the possible shielding properties of BB (Berberrubine) against the harmful auditory effects of cisplatin, preliminarily delving into the underlying mechanisms responsible for this protection.
Methods: HEI-OC1 cell viability was determined using a Cell Counting Kit-8 (CCK-8). The impact of BB on cochlear hair cells was studied through cochlear explants culture.
The therapeutic potential of vitamins A, C, and D in pancreatic cancer.
Heliyon
January 2025
Department of Nutritional Biochemistry, University of Hohenheim, 70599, Stuttgart, Germany.
The pancreatic ductal adenocarcinoma (PDAC) is among the deadliest tumor diseases worldwide. While treatment options have generally become more diverse, little progress has been made in the treatment of PDAC and the median survival time for patients with locally advanced PDAC is between 8.7 and 13.
View Article and Find Full Text PDFHealing the healers: A systematic review on the burden of secondary traumatic stress among healthcare providers.
J Educ Health Promot
December 2024
Mental Health Nursing Department, Symbiosis College of Nursing, Symbiosis International (Deemed University), Pune, Maharashtra, India.
Healthcare professionals (HCPs) are exposed to the traumatic and painful experiences of others as a part of their caring profession, which leaves them vulnerable to developing secondary traumatic stress (STS). It is an occupational hazard for those who provide direct patient care. Systematic review of quantitative studies on secondary traumatic stress among healthcare professionals was published in English between 2013 and 2023, using electronic databases: CINAHL, PubMed, MEDLINE, Global Health, PsychoInfo, and Google Scholar.
View Article and Find Full Text PDFTherapeutic effect of coenzyme-Q10 pretreatment on isoprenaline-induced cardiogenic hepatorenal complications in rats.
Int J Physiol Pathophysiol Pharmacol
December 2024
Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta State University Abraka, Nigeria.
Objectives: The significant correlation between acute myocardial infarction and subsequent hepatorenal dysfunction could result in a higher mortality rate in patients. The study aimed to evaluate the effect and mechanisms of coenzyme-Q10 (Q10) administration on hepatorenal dysfunction in an isoprenaline (ISO)-induced myocardial infarction model in rats.
Materials And Methods: Twenty male rats were assigned into four groups (n = 5).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!