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Amphibian cellular immune response to chytridiomycosis at metamorphic climax.
Immunol Res
January 2025
School of Environment and Science, Griffith University, Southport, QLD, 4222, Australia.
The fungal disease chytridiomycosis (caused by Batrachochytrium dendrobatidis [Bd]) is a primary contributor to amphibian declines. The frog metamorphic stages, characterised by extensive physiological reorganisation and energy expenditure, have heightened susceptibility to Bd. However, little is known about how these metamorphic stages respond immunologically to Bd infection.
View Article and Find Full Text PDFPurpose: Radiation protection glasses reduce eye lens exposure in Interventional Radiology (IR). However, the protection ratio differs for the lead equivalent content and shape of the lenses. This study aimed to examine factors effective in reducing the lens dose by measuring the protection ratio of scattered radiation due to changes in the surgeon's face orientation, various lead equivalents, and shapes.
View Article and Find Full Text PDFSyringic acid protective role: Combatting oxidative stress induced by UVB radiation in L-929 fibroblasts.
J Photochem Photobiol B
January 2025
Post-Graduate Program in Pharmaceutical Sciences, State University of Maringá, Maringá, Paraná, Brazil. Electronic address:
Neglecting proper skin care and repeated exposure to ultraviolet (UV) radiation can have serious consequences, including skin burns, photoaging and even the development of skin cancer. UV radiation-induced damage is mediated by highly unstable and reactive molecules, named reactive oxygen species (ROS). To counteract ROS, the skin has an endogenous antioxidant system.
View Article and Find Full Text PDFScratching promotes allergic inflammation and host defense via neurogenic mast cell activation.
Science
January 2025
Department of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA.
Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates inflammation and whether scratching provides benefit to the host are largely unknown. We found that scratching was required for skin inflammation in mouse models dependent on FcεRI-mediated mast cell activation.
View Article and Find Full Text PDFExploring melatonin's signalling pathways in the protection against age-related skin deterioration.
Pharmacol Rep
January 2025
Razi Drug Research Centre, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Melatonin, renowned for regulating sleep-wake cycles, also exhibits notable anti-aging properties for the skin. Synthesized in the pineal gland and various tissues including the skin, melatonin's efficacy arises from its capacity to combat oxidative stress and shield the skin from ultraviolet (UV)-induced damage. Moreover, it curbs melanin production, thereby potentially ameliorating hyperpigmentation.
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