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The spiritual possession phenomenon (SPP), is a complex transnosological, transcultural syndrome, which is based on the patients' perception that some spiritual entity (spirit, demon, jinn, shaitan, «ikotka», dybbuk, Buddha, etc.) is influencing or possessing them. Modern classifications of diseases, aimed at expanding our ideas about the distinction between the norm and pathology of mental disorders, do not contribute to a clear psychopathological differentiation of SPP, the determination of its nosological affiliation and the choice of appropriate therapeutic tactics for these conditions.

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Could Be a Promising Marker for Preoperative Diagnosis of High-Grade Papillary Thyroid Carcinoma?

Diagnostics (Basel)

November 2024

Department of the Structure and Function of Chromosomes, Institute of Molecular and Cellular Biology, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.

Background/objectives: A modern classification distinguishes between two nosological entities posing an intermediate risk between differentiated and anaplastic carcinoma: poorly differentiated thyroid carcinoma and differentiated high-grade thyroid carcinoma. There are currently few studies searching for the preoperative molecular genetic markers of high-grade papillary thyroid carcinoma (PTC HG), primarily because of a recent WHO reclassification and singling out of a separate entity: high-grade follicular cell-derived nonanaplastic thyroid carcinoma. Therefore, this work was aimed at identifying PTC HG-specific microRNAs and mRNAs that reliably distinguish them from differentiated papillary thyroid carcinoma in preoperative cytology specimens (fine-needle aspiration biopsies).

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Genome sequencing in the management of myelodysplastic syndromes and related disorders.

Haematologica

October 2024

Department of Molecular Medicine, University of Pavia, and Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia.

Article Synopsis
  • * Significant research has reshaped the understanding of MDS, uncovering key mutations in important genes and helping categorize the disease into distinct types based on these genetic changes.
  • * Advances in genomic profiling and the Molecular International Prognostic Scoring System (IPSS-M) are enhancing diagnosis and treatment personalization, emphasizing the need for collaborative efforts in healthcare and research.
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[Mechanisms of prolonged symptoms following acute COVID-19: Some pathophysiological pathways].

Rev Mal Respir

November 2024

Service des maladies infectieuses et tropicales, CHU d'Angers, 4, rue Larrey, 49100 Angers, France. Electronic address:

Introduction: Following the Omicron wave in early 2022, an estimated 60-70% of the French population was infected with the SARS-CoV-2 virus. One out of ten infected subjects could have persistent symptoms three months after infection, representing a public health challenge.

Current State Of Knowledge: The persistent symptoms may be secondary to diverse entities with distinct mechanisms.

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Seizures and Epilepsy in Association With Neurocysticercosis: A Nosologic Proposal.

Neurology

November 2024

From the Department of Neurology (G.S.), Dayanand Medical College & Hospital, Ludhiana, India; Center for Global Health and School of Sciences (H.H.G.), Universidad Peruana Cayetano Heredia; Cysticercosis Unit (H.H.G.), Instituto Nacional de Ciencaia Neurologicas, Lima, Peru; School of Medicine and Research Center (O.H.D.B.), Universidad Espiritu Santo-Ecuador, Samborondón; Albert Einstein College of Medicine (C.C.), Bronx, NY; Department of Clinical & Experimental Epilepsy (J.W.S.), UCL Queen Square Institute of Neurology, London; and Chalfont Centre for Epilepsy (J.W.S.), Chalfont St Peter, United Kingdom.

Article Synopsis
  • Neurocysticercosis is a big cause of seizures and epilepsy in some areas of the world that struggle to control the infection.
  • Many of the seizures caused by this infection are called "acute symptomatic seizures," but this name isn't really right because the condition isn't just temporary.
  • The text suggests that seizures should be classified based on the stage of the infection and also points out that there are other health issues related to neurocysticercosis that need to be recognized.
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