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[Effects of small ionizing radiation doses on hemato-encephalic barrier permeability].
Aviakosm Ekolog Med
April 2014
Goal and objectives of the study was comparative description and establishment of dose-time dependence of changes in permeability of the hemato-encephalic barrier (HEB) in phylogenetically different parts of the brain cortex, i.e. new (Fr2 and Cg3), old (hippocampal fields CA1-CA4 and dentate fascia) and paleocortex (piriform cortex) following exposure to 0.
View Article and Find Full Text PDFEosinophil-induced prognosis improvement of solid tumors could be enabled by their vesicle-mediated barrier permeability induction.
Med Hypotheses
May 2008
Mother Theresa School of Medicine, Department of Allergology and Clinical Immunology, Rruga Myslym Shyri, P. 47, Ap. 15 Tirana, Albania.
Eosinophils are multifunctional cells, which contain and produce many biologically active substances. Generally, eosinophilia is associated with parasitic infections or allergic disorders, while according to recent studies eosinophil infiltration is also present in target tissues of both physiological and pathological processes, such as angiogenesis, embryogenesis, immune regulation, different infections or neoplasies, leading to tissue damage or remodeling. Reflecting on prognosis improvement in the case of solid tumors after eosinophilic infiltration of their capsules, it could be hypothesized that eosinophils are not tumoricidal per se; rather they can perforate such barriers through their vesicles' content, whereas the tumoricidal cytokines such as interleukin 4 (IL-4) fulfill the tumoral necrosis.
View Article and Find Full Text PDF[Cerebral edema and its treatment].
Medicina (Kaunas)
April 2007
Clinic of Intensive Care, Kaunas University of Medicine, Kaunas, Lithuania.
Cerebral edema is a life-threatening condition that develops as a result of an inflammatory reaction. Most frequently, this is the consequence of cerebral trauma, massive cerebral infarction, hemorrhages, abscess, tumor, allergy, sepsis, hypoxia, and other toxic or metabolic factors. At present, the following types of cerebral edema are differentiated: the vasogenic cerebral edema resulting from an increased permeability of the endothelium of cerebral capillaries to albumin and other plasma proteins; the cytotoxic cerebral edema resulting from the exhaustion of the energy potential of cell membranes without damage to the barrier; the hydrostatic cerebral edema resulting from disturbance of the autoregulation of cerebral blood circulation; the osmotic cerebral edema resulting from dilution of blood; and the interstitial cerebral edema resulting from acute hydrocephaly.
View Article and Find Full Text PDF[The formation of neurons in the bone marrow, the dream of alchemy in the new millenium].
Morphologie
March 2003
Laboratoire d'Histologie et Embryologie, UMR CNRS 7000, Faculté de Médecine Pitié-Salpêtrière, Université Paris 6, 105, Boulevard de l'Hôpital, 75634 Paris, France.
In rodents, bone marrow contains stem cells that have the potentiality to differentiate into mesodermal and non-mesodermal cells, both in vitro and in vivo. These cells can populate a wide panel of organs such as the liver, the brain, the lungs, the heart..
View Article and Find Full Text PDF[Permeability of hemato-encephalic barrier in Alzheimer's disease and parkinsonism with cognitive disorders].
Zh Nevrol Psikhiatr Im S S Korsakova
October 2001
The study was made of 17 patients with expected Alzheimer's disease (AD), 29 patients with Parkinson's disease (PD) and 7 with a expected dementia with Levy bodies (DLB). The severity of cognitive disorders was determined according to the following scales: Global Deterioration Rating Scale, Mini-mental State Examination, Mattis Dementia Rating Scale. Besides, the patients state was evaluated, in the whole, according to some scales.
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