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Bone and vascular effects of magnesium supplements in CKD patients (the MagicalBone Pilot Study).
Nefrologia (Engl Ed)
November 2024
Nephrology Service, Reina Sofia University Hospital, Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), University of Cordoba, Spain; RICORS2040, Madrid, Spain.
Background And Objective: The progression of chronic kidney disease (CKD) involves the development of alterations in mineral metabolism that are closely related to cardiovascular outcomes and bone disease. Hypomagnesemia is associated with more rapid progression of CKD and other comorbidities. Our objective was to analyze in CKD patients stages 3-4 the impact of the administration of magnesium (Mg) carbonate on bone mineral density (BMD) and hemodynamic changes associated with by vascular calcification (VC).
View Article and Find Full Text PDFWhole brain pattern of iron accumulation in REM sleep behavior disorder.
Hum Brain Mapp
April 2024
Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic.
Isolated REM sleep behavior disorder (iRBD) is an early stage of synucleinopathy with most patients progressing to Parkinson's disease (PD) or related conditions. Quantitative susceptibility mapping (QSM) in PD has identified pathological iron accumulation in the substantia nigra (SN) and variably also in basal ganglia and cortex. Analyzing whole-brain QSM across iRBD, PD, and healthy controls (HC) may help to ascertain the extent of neurodegeneration in prodromal synucleinopathy.
View Article and Find Full Text PDFDiagnosis and staging of small intestinal neuroendocrine tumors with CT enterography and PET with Gallium-68: preoperative risk stratification protocol.
Langenbecks Arch Surg
February 2024
Digestive Surgery, European Institute of Oncology, IRCCS, Via Ripamonti 435, Milan, Italy.
Purpose: Pre-operative diagnosis and staging of small intestine neuroendocrine tumors (SI-NETs) remain sub-optimal, with open palpation during surgery still considered the gold standard. This limits a standardized implementation of minimally invasive surgery (MIS). The aim of this single-center retrospective study was to assess a tailored diagnostic work-up to identify candidates at low risk of undetected disease who may benefit from MIS.
View Article and Find Full Text PDFRecommendations for the management of yttrium-90 radioembolization in the treatment of patients with colorectal cancer liver metastases: a multidisciplinary review.
Clin Transl Oncol
April 2024
Instituto de Investigación Biosanitaria IBS, Granada, Spain.
Article Synopsis
- The study focuses on the evolving treatment strategies for liver metastases from colon cancer, highlighting the role of Yttrium-90 Radioembolization (Y-90 TARE) as a viable option for patients with unresectable liver metastases.
- A multidisciplinary committee of experts conducted a thorough literature review to create recommendations on the use of Y-90 TARE, addressing criteria like patient selection, treatment indications, and potential contraindications.
- The review provides a detailed framework for implementing Y-90 TARE, covering essential areas from initial patient evaluation to post-treatment follow-up, ensuring comprehensive management of the treatment process.
Vitamin D intoxication: myth or reality.
Minerva Med
October 2023
Unit of Diagnostic and Interventional Radiology, Department of Radiology, Maggiore Polyclinic Hospital, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
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