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Effect of Ischemic Postconditioning on Myocardial Function and Infarct Size Following Reperfusion Injury in Diabetic Rats Pretreated With Vildagliptin.
J Cardiovasc Pharmacol Ther
March 2018
1 Physiology Laboratory, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Cardioprotective actions of ischemic postconditioning (IPostC) against ischemia/reperfusion (I/R) injury are abolished in diabetic hearts. This study has investigated the combined effects of IPostC and vildagliptin (Vilda) on myocardial function and infarct size (IS) against I/R injury in diabetic myocardium.
Methods: Diabetes was induced by a high-fat diet/low dose of streptozotocin (35 mg/kg; intraperitoneally) in Wistar rats (200-250 g) and lasted for 12 weeks.
Direct-Contact Low-Frequency Ultrasound Clearance of Biofilm From Metallic Implant Materials.
Eplasty
March 2017
Department of Oral Biology, Rutgers New Jersey Dental School, Newark.
Biofilms are recognized as a significant deterrent to wound healing and to the management of exposed or infected surgical implants. Biofilms can be disrupted by a variety of enzymatic and mechanical interventions. This experiment was designed to determine whether direct-contact low-frequency ultrasound has the ability to clear biofilms and what then happens to the released bacteria.
View Article and Find Full Text PDFProcessing Adipose-Rich Mohs Samples: A Comparative Study of Effectiveness of Pretreatment With Liquid Nitrogen Versus Flash Freezing Spray.
Am J Dermatopathol
November 2017
*Division of Dermatology, Loyola University Medical Center, Maywood, IL; †Stritch School of Medicine, Loyola University Medical Center, Maywood, IL; ‡Department of Pathology, Loyola University Medical Center, Maywood, IL; and §Division of Health Sciences, Loyola University Chicago, Maywood, IL.
Processing of adipose-rich Mohs micrographic surgery (MMS) specimens poses challenges that may preclude complete margin evaluation. In this setting, the value of additional freezing methods using various cooling agents has not been previously investigated. The aim of this study is to compare the frozen section quality of high-adipose Mohs specimens processed without additional cooling treatments versus those pretreated with 1,1,1,2-tetrafluoroethane (TFE) or liquid nitrogen (LN2).
View Article and Find Full Text PDFExpression and Distribution of Calcium-Binding Protein S100P in Human Placenta during Pregnancy.
Int J Fertil Steril
March 2015
Assisted Reproduction Unit, Department of Obstetrics and Gynecology , Sir Run Run Show Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Background: S100P is a member of the S100 family of calcium-binding proteins, and it participates in pathophysiological events, such as tumor growth and invasion. Based on the striking similarities between trophoblast cells and tumor cells with regard to proliferative and invasive properties, we raised the question of whether and how S100P expresses in trophoblast cells during development. This study aimed to investigate the expression pattern of S100P in the human placenta during pregnancy development.
View Article and Find Full Text PDFReverse lymphatic mapping: a new technique for maximizing safety in vascularized lymph node transfer.
Plast Reconstr Surg
January 2015
New York, N.Y. From Beth Israel Medical Center.
Background: The authors introduce the technique of reverse lymphatic mapping for vascularized lymph node transfer. This physiologic technique allows one to identify which lymph nodes drain the trunk as opposed to the extremity, to minimize the risk of iatrogenic lymphedema.
Methods: A prospective study of patients undergoing vascularized lymph node transfer using the reverse lymphatic mapping technique was conducted.
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