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Effects of tropical fruit blends on fermentative and pigmentation aspects of probiotic native cultured goat milk.
PeerJ
January 2025
Centro de Tecnologia e Desenvolvimento Regional, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil.
Background: Fruits are sources of bioactive compounds such as phenolics that bring health benefits to consumers. The addition of fruit products and microorganisms with probiotic potential in fermented goat milk can facilitate the acquisition of these benefits through diet. In this sense, the objective of this study was to evaluate the effect of incorporating a mixture of ingredients from jaboticaba (), jambolana (), and mandacaru () fruits on fermentation parameters (pH, titratable acidity, viability of the native culture CNPC003 and the starter culture), associated with pigmentation (phenolic compound content and color) through experimental mixture design.
View Article and Find Full Text PDFSimulating large molecular systems over long timescales requires force fields that are both accurate and efficient. In recent years, E(3) equivariant neural networks have lifted the tension between computational efficiency and accuracy of force fields, but they are still several orders of magnitude more expensive than established molecular mechanics (MM) force fields. Here, we propose Grappa, a machine learning framework to predict MM parameters from the molecular graph, employing a graph attentional neural network and a transformer with symmetry-preserving positional encoding.
View Article and Find Full Text PDFBiomechanical evaluation of different fixation techniques in the rotation of the maxillary occlusal plane after Le Fort I osteotomy.
J Clin Exp Dent
December 2024
Faculty of Dentistry of Pernambuco, University of Pernambuco, 50100130, Recife, Pernambuco, Brasil.
Background: To analyze the biomechanical and functional characteristics of different maxillary fixation techniques after Le Fort I osteotomy and occlusal plane rotation, using the finite element method to simulate the mechanical behavior of three different osteosynthesis approaches.
Material And Methods: This is a virtual experimental study carried out using finite element analysis to compare three different osteosynthesis techniques after Le Fort I osteotomy and rotation of the maxillary occlusal plane. Three configurations were tested: four-point fixation with "L" plates (C1), two-point fixation with "L" plates (C2), and two-point fixation with pre-modeled Lindorf plates (C3).
Seizure network characterization by functional connectivity mapping and manipulation.
Neurophotonics
January 2025
Weill Cornell Medicine, Department of Neurological Surgery, New York, United States.
Significance: Despite the availability of various anti-seizure medications, nearly 1/3 of epilepsy patients experience drug-resistant seizures. These patients are left with invasive surgical options that do not guarantee seizure remission. The development of novel treatment options depends on elucidating the complex biology of seizures and brain networks.
View Article and Find Full Text PDFPsychometrics of Wearable Devices Measuring Physical Activity in Ambulant Children With Gait Abnormalities: A Systematic Review and Meta-analysis.
Arch Rehabil Res Clin Transl
December 2024
Research Centre Healthy and Sustainable Living, Research group Lifestyle and Health, Utrecht University of Applied Sciences, Utrecht, The Netherlands.
Objective: To evaluate psychometrics of wearable devices measuring physical activity (PA) in ambulant children with gait abnormalities due to neuromuscular conditions.
Data Sources: We searched PubMed, Embase, PsycINFO, CINAHL, and SPORTDiscus in March 2023.
Study Selection: We included studies if (1) participants were ambulatory children (2-19y) with gait abnormalities, (2) reliability and validity were analyzed, and (3) peer-reviewed studies in the English language and full-text were available.
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