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Transdermal electrophysiological recordings of diet-induced small fiber peripheral neuropathy using a needle electrode array in mice and man.
Front Bioeng Biotechnol
January 2025
Department of Neurological Surgery, The Ohio State University, Columbus, OH, United States.
Background: Diabetic peripheral neuropathy (DPN) is a common complication of diabetes. Proactive treatment options remain limited, which is exacerbated by a lack of sensitive and convenient diagnostics, especially early in disease progression or specifically to assess small fiber neuropathy (SFN), the loss of distal small diameter axons that innervate tissues and organs.
Methods: We designed, fabricated, tested, and validated a first-of-its-kind medical diagnostic device for the functional assessment of transdermal small fiber nerve activity.
Patient Perspectives on Home Tonometer Usage for Glaucoma.
Clin Ophthalmol
January 2025
Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA.
Purpose: To understand patient experiences using the iCare HOME tonometer through assessing ease of use, device usage patterns, proficiency, and patient comments.
Methods: We conducted a prospective survey-based cohort study of 19 patients (35 eyes) with glaucoma or glaucoma suspect diagnoses. Patients received training on home tonometer usage and were loaned the device for one week to measure intraocular pressure at home multiple times daily.
SERS profiling of blood serum filtrate components from patients with type II diabetes using 100 kDa filtration devices.
RSC Adv
January 2025
Département de Chimie, Faculté des Sciences et de Génie, Université Laval Québec QC G1V 0A6 Canada.
Blood carries some of the most valuable biomarkers for disease screening as it interacts with various tissues and organs in the body. Human blood serum is a reservoir of high molecular weight fraction (HMWF) and low molecular weight fraction (LMWF) proteins. The LMWF proteins are considered disease marker proteins and are often suppressed by HMWF proteins during analysis.
View Article and Find Full Text PDFA Rare Presentation of Bacteremia Secondary to Skin and Soft Tissue Infection.
J Community Hosp Intern Med Perspect
January 2025
University Maryland Medical Center Midtown Campus, Department of Internal Medicine, USA.
is a rod-shaped, flagellated, non-lactose fermenting, gram negative bacterium, usually found in water and soil habitats. generally causes nosocomial infections in immunocompromised patients. Increased infection rates are seen in those patients with medical devices inserted, due to this organism's innate ability to attach to moist and inanimate objects.
View Article and Find Full Text PDFFactors associated with male acceptance of modern contraceptive methods. A descriptive cross-sectional study in a peri-urban municipality.
Contracept Reprod Med
January 2025
Department of Public Health Nursing, School of Nursing and Midwifery, University of Health and Allied Sciences, PMB 31, Ho, Volta Region, Ghana.
Background: Male knowledge and acceptance of modern contraceptive use play a significant role in uptake. This study assessed the factors associated with male acceptance of modern contraceptive methods in Ho Municipality.
Methods: A cross-sectional study with a quantitative approach was employed.
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