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Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways.
Mar Drugs
January 2025
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Inflammatory bowel disease (IBD) is characterized by uncontrolled, chronic relapsing inflammation in the gastrointestinal tract and has become a global healthcare problem. Here, we aimed to illustrate the anti-inflammatory activity and the underlying mechanism of methyl 3-bromo-4,5-dihydroxybenzoate (MBD), a compound derived from marine organisms, especially in IBD, using a zebrafish model. The results indicated that MBD could inhibit the inflammatory responses induced by CuSO, tail amputation and LPS in zebrafish.
View Article and Find Full Text PDFfor targeting MRSA virulence: and studies.
Heliyon
January 2025
Department of Biological Sciences, Faculty of Science, Beirut Arab University, Tripoli, 1300, Lebanon.
The present study reports the characterization of the phytochemical content and the antibacterial activity of ethanolic extracts from the leaves (LE) and stems (SE) of against Methicillin resistant (MRSA. Important functional groups were determined by analyzing the FTIR spectra of LE and SE. The phytochemical profiles were analyzed by GC-MS, and these characterized the chemicals according to retention periods and peak regions.
View Article and Find Full Text PDFMicrobiota dynamics and metabolic mechanisms in fermented sausages inoculated with Lactiplantibacillus plantarum and Staphylococcus xylosus.
Food Res Int
February 2025
China Light Industry Key Laboratory of Meat Microbial Control and Utilization, Hefei University of Technology, Hefei 230009, China; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Hefei 230601, China. Electronic address:
Lactiplantibacillus plantarum and Staphylococcus xylosus are common starters for fermented sausages. Several studies have demonstrated the impact of these two strains on the quality of fermented sausages. However, the mechanism underlying the effects of these two microorganisms on co-cultivation in sausages remains unclear.
View Article and Find Full Text PDFVisible light induced photocatalytic degradation of norfloxacin using xC-TiO.
Heliyon
January 2025
Institute of Chemical Sciences, University of Swat, Swat, 19120, Khyber Pakhtunkhwa, Pakistan.
In recent years, antibiotic pollution has become a major environmental concern. The extensive production and widespread use of prescribed antibiotics have significantly impacted ecosystems. The main objective of the present study is to investigate the photocatalytic degradation of the antibiotic norfloxacin (NFX) under visible light.
View Article and Find Full Text PDFMesoporous Silica Nanoparticle Rigid Anchor Attached Pt Complex for Catalytic H/D Exchange of Aromatic Substrates.
Inorg Chem
January 2025
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States.
A Pt(II) aqua complex supported by mesoporous silica nanoparticle (MSN)-immobilized sulfonated CNN pincer ligand featuring a rigid SiO tether was prepared. This hybrid material was tested as a catalyst in H/D exchange reactions of C(sp)-H bonds of selected aromatic substrates and DO-2,2,2-trifluoroethanol- (TFE-) mixtures or CDCOD acting as a source of exchangeable deuterium. The catalyst immobilization served as a means to not only enable the catalyst's recyclability but also minimize the coordination of sulfonate groups and the metal centers originating from different catalyst's moieties that would preserve reactive Pt(OH) fragments needed for catalytic C-H bond activation.
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