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HEALTH-RELATED QUALITY OF LIFE OF CHILDREN WITH AND WITHOUT SICKLE CELL ANAEMIA AT EDWARD FRANCIS SMALL TEACHING HOSPITAL, THE GAMBIA.
West Afr J Med
November 2024
Department of Paediatrics, Edward Francis Small Teaching Hospital, Banjul, The Gambia. E-mail:
Article Synopsis
- Children with sickle cell anaemia (SCA) experience worse health-related quality of life (HRQoL) compared to healthy children, especially in physical, emotional, and social aspects.
- The study, involving 130 children aged 5-15 in The Gambia, found that many SCA patients had poor HRQoL scores, with 57.7% rated as poor.
- Significant factors like frequent pain experiences, late diagnosis, and clinical stroke were linked to lower HRQoL, highlighting the need for better management and support for children with SCA.
Clinico-Laboratory Profile of Tuberculides: An Experience at a Tertiary Care Centre from Chandigarh, India.
Indian J Dermatol
April 2024
From the Department of Dermatology, Venereology and Leprology, Government Medical College and Hospital, Chandigarh, Punjab, India.
Article Synopsis
- Tuberculides are immune reactions to tuberculosis that occur in healthy individuals, and this study focuses on their characteristics and treatment responses in a North Indian healthcare center.
- Analyzing clinical records from 2000 to 2019, the study identified 34 patients with tuberculides, with lichen scrofulosorum being the most prevalent type, followed by other forms like erythema nodosum.
- The findings highlight that tuberculides can indicate hidden tuberculosis infections, aiding in early diagnosis and effective treatment with a standard six-month anti-tubercular therapy regimen.
Central nervous system involvement in multiple myeloma: Experience from a tertiary cancer center and review of literature.
Indian J Cancer
April 2023
Department of Oncopathology, Cancer Institute (W.I.A.), Adyar, Chennai - 600020, India.
Background: Multiple myeloma (MM) results from clonal expansion of immunoglobulin secreting, heavy chain class-switched, terminally differentiated B-lymphocytes (plasma cells), resulting in radiologic or biochemical evidence of end-organ damage. Though neurological manifestations (peripheral neuropathies, spinal radiculopathies, cranial nerve palsies, and metabolic encephalopathies) can occur during the disease course, direct central nervous system (CNS) infiltration by malignant plasma cells (CNS-MM) is very rare (~1%) and has a dismal prognosis (survival of <6 months).
Methodology: Clinico-laboratory profile and outcome of CNS-MM patients diagnosed and treated at a tertiary cancer care hospital were retrospectively analyzed.
Dermoscopy of Oral Mucosal Lesions: Experience from a Tertiary Care Center in North India and Review of Literature.
Indian Dermatol Online J
May 2022
Department of Dermatology, Venereology and Leprosy, Government Medical College, Srinagar, University of Kashmir, Jammu and Kashmir, India.
Background: Patients with mucosal lesions form a significant number of routine outpatients presenting to the dermatology department where diagnostic confirmation using histopathological examination of mucosal biopsy is neither feasible nor warranted in every patient.
Objective: To study the dermoscopic features of various mucosal lesions affecting the oral cavity and to assess the reliability of mucoscopy vis-a-vis clinico-laboratory findings.
Materials And Methods: An observational, cross-sectional, hospital-based study was conducted over a period of 2 years from March 2019 to February 2021 in the dermatology outpatient department.
Clinico-Laboratory Profile, Intensive Care Needs and Short-Term Outcome of Multisystem Inflammatory Syndrome in Children (MIS-C): Experience during First and Second Waves from North India.
J Trop Pediatr
August 2022
Division of Pediatric Emergency and Intensive Care, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India.
Objectives: To describe the clinico-laboratory profile, intensive care needs and outcome of multisystem inflammatory syndrome in children (MIS-C) during the first and second waves.
Methodology: This retrospective study was conducted in the paediatric emergency and paediatric intensive care unit (PICU) of a tertiary care teaching hospital in North India involving 122 children with MIS-C admitted during the first wave (September 2020-January 2021, n = 40) and second wave (February 2021-September 2021, n = 82) of coronavirus disease 2019 (COVID-19).
Results: The median (interquartile range) age was 7 (4-10) years and 67% were boys.
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