From 1985 to 1990 we saw 318 patients with polymorphous light eruption (PLE). Papular (47.4%) and papular-vesicular (27.2%) skin lesions were predominant. A monomorphous picture was seen in 31%. The first lesions appeared within a median period of 19 h after sun exposure, and in 38% of cases within 5 h. In most patients (78.7%) the skin eruptions faded within 1 week of appearance (median 4 days). There seems to be a correlation between the course of light exposure and the resulting clinical morphology. Terminological and methodical problems in the classification of PLE are discussed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Photopatch testing: Clinical characteristics, test results, and final diagnoses from the North American Contact Dermatitis Group, 2009-2020.
Contact Dermatitis
December 2024
Department of Dermatology, University of Colorado, Aurora, Colorado, USA.
Article Synopsis
- Photoallergic contact dermatitis (PACD) is a hypersensitivity reaction triggered by allergens only when exposed to UV light, requiring photopatch testing (PhotoPT) for diagnosis.* -
- A study from 2009-2020 involving 454 patients revealed that most were women, aged 21-60, and the majority were White; results showed 119 positive tests, predominantly related to sunscreen agents like benzophenones.* -
- Among the diagnosed conditions, approximately 17.2% of patients had PACD, while other diagnoses included allergic contact dermatitis, polymorphous light eruption, and chronic actinic dermatitis, highlighting the need for photopatch testing in these cases.*
[Solar urticaria and polymorphous light eruption].
Dermatologie (Heidelb)
July 2024
Zentrum für Dermatologie, Allergologie und Dermatochirurgie, Helios Universitätsklinikum Wuppertal, Wuppertal, Deutschland.
Article Synopsis
- Solar urticaria is a rare skin condition triggered by UV radiation or visible light, likely caused by an allergic reaction, leading to severe symptoms that significantly affect patients' quality of life.
- Polymorphous light eruption, in contrast, is a more common condition resulting from a type IV allergic reaction to photoallergens, with skin lesions that heal despite sun exposure and generally less impact on quality of life.
- Both conditions are diagnosed through light provocation and can benefit from a treatment approach called light hardening, highlighting their distinct clinical features and management strategies.
Tofacitinib: A Treatment Option for Recalcitrant Polymorphic Light Eruption and Its Mechanistic Rationale.
Dermatitis
June 2024
From the Department of Dermatology, Venereology and Leprosy, ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Article Synopsis
- - Polymorphous light eruption is an allergic skin reaction triggered by sunlight, and it involves a type IV hypersensitivity to unknown skin antigens caused by UV exposure.
- - A study assessed the effectiveness of tofacitinib in seven patients who had not responded to other treatments; results showed significant relief from itching and faster healing.
- - Tofacitinib works by inhibiting certain enzymes (JAK1 and JAK3) that contribute to inflammation, helping to lower the overactive immune response seen in polymorphous light eruption.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!