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The influence of habitat complexity on otolith morphology and sensory capacities in Nile tilapia: A controlled experimental approach.
J Exp Biol
January 2025
Laboratory of Function and Evolutionary Morphology, FOCUS, Université de Liège, Liège, Belgique.
The inner ear of teleost fishes is known to serve both auditory and vestibular functions. Many studies have compared otoliths from different species and attempted to understand the observed differences within the light of environmental factors. However, experimental data on how otoliths could adapt are scarce.
View Article and Find Full Text PDFRapid acclimatization to baseline stimulation with a multi-canal vestibulocochlear implant.
Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, School for Mental Health and Neuroscience (MHENS), Maastricht University Medical Centre, Maastricht, The Netherlands.
Purpose: It is hypothesized that a vestibular implant should re-establish baseline activity of the ampullary nerves. Use of a constant baseline stimulation potentially allows encoding of bi-directional head movements, through the addition of signal modulations. Effective stimulation of the vestibular nerves depends on the ability to acclimate to this baseline signal.
View Article and Find Full Text PDFHair cells (HCs) are essential for vestibular function, and irreversible damage to vestibular HCs in mammals is closely associated with vertigo. The stimulation of HC regeneration through exogenous gene delivery represents an ideal therapeutic approach for restoring vestibular function. Overexpression of Atoh1, Pou4f3, and Gfi1 (collectively referred to as APG) has demonstrated efficacy in promoting HC regeneration in the cochlea.
View Article and Find Full Text PDFVestibular nerve neurectomy: Functional and histopathological outcomes in the cochlea of guinea pigs.
Auris Nasus Larynx
January 2025
Otorhinolaryngology and Head and Neck Surgery Department Ain Shams University Faculty of Medicine, Egypt. Electronic address:
Objectives: Experimentally test the effect of vestibular nerve neurectomy on the function and histopathology of the cochlea.
Methods: The study was conducted on 20 normal male adult pigmented guinea pigs (Cavia porcellus). First, each animal was tested with Distortion Product Otoacoustic Emissions (DPOAEs) preoperatively then vestibular neurectomy (V.
Audiometric Outcomes of Auditory Brainstem Implantation during Vestibular Schwannoma Resection in NF2 Patients.
J Neurol Surg B Skull Base
February 2025
Department of Neurosurgery, UC San Diego Medical Center, San Diego, California, United States.
Many patients with neurofibromatosis type 2 (NF2) suffer from sensorineural hearing loss, and associated cochlear nerve compromise in NF2 patients makes auditory brainstem implant (ABI) an attractive treatment option. The long-term outcomes and benefits of the device are still being explored. A retrospective review was conducted for 11 ABI recipients at a single-institution tertiary center between November 2017 and August 2022.
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