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Coinfection of cytomegalovirus and strongyloidiasis presenting as massive gastrointestinal bleeding in an immunocompromised host: a case report.
Front Med (Lausanne)
November 2024
Department of Gastroenterology, 108 Military Central Hospital, Hanoi, Vietnam.
Cytomegalovirus (CMV) infection is an opportunistic disease in immunocompromised patients that may appear without symptoms, with constitutional symptoms, or as a tissue-invasive disease. infection often manifests with non-specific symptoms; however, it can lead to severe malabsorption and extraintestinal dissemination by accelerated autoinfection. The coinfection of CMV and has rarely been reported, particularly with solely severe gastrointestinal bleeding.
View Article and Find Full Text PDFReview of the WHO guideline on preventive chemotherapy for public health control of strongyloidiasis.
Lancet Infect Dis
October 2024
Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland.
Article Synopsis
- Strongyloidiasis is a widespread parasitic infection affecting 300-600 million people, particularly in tropical regions, and poses serious health risks, especially during immunosuppression, with high fatality rates.
- There have been no significant global health initiatives targeting this disease until recently, when the WHO included it in their roadmap for controlling neglected tropical diseases, highlighting its importance.
- The new WHO guidelines recommend mass drug administration of ivermectin in areas with a prevalence of over 5%, aiming for effective public health strategies to combat strongyloidiasis.
Strongyloidiasis.
Nat Rev Dis Primers
January 2024
Population Health Program, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
Strongyloidiasis is a neglected tropical disease caused primarily by the roundworm Strongyloides stercoralis. Strongyloidiasis is most prevalent in Southeast Asia and the Western Pacific. Although cases have been documented worldwide, global prevalence is largely unknown due to limited surveillance.
View Article and Find Full Text PDF[miRNA Expression Profile in Ileocecal Adenocarcinoma Cells Infected with Cryptosporidium].
Mikrobiyol Bul
July 2022
Ege University Institute of Health Sciences, Department of Basic Oncology, İzmir, Türkiye.
Cryptosporidium spp. is an opportunistic protozoan transmitted by fecal-oral route via oocysts. The agent may cause severe infection especially in individuals with suppressed immune system, due to its intracellular location and ability to cause auto-infection.
View Article and Find Full Text PDFSystemic profile of immune factors in an elderly Italian population affected by chronic strongyloidiasis.
Parasit Vectors
October 2020
Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Article Synopsis
- Strongyloidiasis, caused by the parasite Strongyloides stercoralis, affects around 370 million people globally and persists lifelong due to its unique infection cycle, even with documented cases in areas like north-eastern Italy where transmission has ceased.
- Researchers analyzed serum levels of 23 immune factors in Italian patients treated for strongyloidiasis, comparing pre-treatment levels to post-treatment levels and uninfected controls, to understand the immune response to the infection.
- The study found that patients with strongyloidiasis had lower levels of certain chemokines, indicating impaired immune response, while post-treatment showed an increase in specific growth factors, suggesting some restoration of immune function. *
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