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Targeted nutritional strategies in postoperative care.
Anesth Pain Med (Seoul)
January 2025
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Immunonutrition, which uses specific nutrients to modulate the immune response, has emerged as a vital adjunct to perioperative care. Surgery-induced stress triggers immune responses that can lead to complications, such as infections and delayed wound healing. Traditional nutritional support often overlooks the immunological needs of surgical patients.
View Article and Find Full Text PDFShenqi injection plus probiotics improves nutritional status in patients with gastric cancer after partial gastrectomy.
Pak J Pharm Sci
January 2025
Department of Gastroenterology, Yulin First Hospital, Yulin, Shaanxi, China.
In recent years, the incidence of gastric cancer (GC) has been on the rise, surgical procedures usually require the removal of part of gastric tissue connected with the tumor lesion, which leads to poor postoperative health and adverse prognosis in patients. Probiotics, as an active microorganism, play an important role in improving gastrointestinal function and enhancing immunity. In this study, we randomized 135 GC patients into a control group, a probiotic group and a combination group.
View Article and Find Full Text PDFThe Gut in Critical Illness.
Curr Gastroenterol Rep
December 2025
Division of Pulmonary, Critical Care, and Sleep Medicine, Medical College of Wisconsin, 8701 West Watertown Plank Road, 8th Floor: HUB for Collaborative Medicine, Milwaukee, WI, 53226, USA.
Purpose Of Review: The purpose of this narrative review is to describe the mechanisms for gut dysfunction during critical illness, outline hypotheses of gut-derived inflammation, and identify nutrition and non-nutritional therapies that have direct and indirect effects on preserving both epithelial barrier function and gut microbiota during critical illness.
Recent Findings: Clinical and animal model studies have demonstrated that critical illness pathophysiology and interventions breach epithelial barrier function and convert a normally commensal gut microbiome into a pathobiome. As a result, the gut has been postulated to be the "motor" of critical illness and numerous hypotheses have been put forward to explain how it contributes to systemic inflammation and drives multiple organ failure.
Immunonutrition in Operated-on Gastric Cancer Patients: An Update.
Biomedicines
December 2024
Hellenic Society for Gastrointestinal Oncology, Iera Odos 354, Haidari, 12461 Athens, Greece.
Enteral immune nutrition has attracted considerable attention over the past few years regarding its perioperative role in patients undergoing major surgery for digestive cancer. Today, the term enteral immune nutrition refers to the perioperative administration of nutritional preparations containing, among others, specific ingredients such as glutamine, omega-3 polyunsaturated fatty acids, and arginine. They provide nutritional support and exert pharmacological effects through the substances contained in these preparations.
View Article and Find Full Text PDFResearch progress on digestive disorders following traumatic brain injury.
Front Immunol
January 2025
Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Article Synopsis
- Traumatic brain injury (TBI) is a significant global health issue, leading to digestive dysfunction that complicates recovery and health outcomes.
- The mechanisms affecting digestion post-TBI include inflammation, the enteric nervous system, and hormonal changes, all of which can hinder neurologic recovery through the brain-gut axis.
- The article explores the pathogenesis of digestive issues after TBI, aiming to enhance treatment strategies and the long-term prognosis for patients by improving digestive function through recent technological advancements.
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