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Development of high-strength, 3D-printable, and biocompatible gelatin/κ-carrageenan dual-network hydrogels for wound healing.
Int J Biol Macromol
January 2025
The Affiliated Qingyuan Hospital (Qingyuan People's Hospital), Guangzhou Medical University, Qingyuan, Guangdong Province 511518, China. Electronic address:
Gelatin/κ-carrageenan (Gel/KC) hydrogel has exhibited a significant potential in tissue engineering, however, there is still a need to further enhance its structural properties. This study developed a Gel/KC dual-network hydrogel with superior mechanical properties and structural stability, which was integrated with 3D printing to evaluate its ability to promote wound healing. The hydrogels with seven different Gel and KC ratios were prepared and characterized using rheological testing, thermal analysis, spectral analysis, micromorphology observation, and X-ray diffraction.
View Article and Find Full Text PDFHyperspectral Imaging for High Throughput Optical Spectroscopy of pL Droplets.
Anal Chem
January 2025
Nanophotonic Systems Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.
Droplet-based microfluidics is a powerful tool for high-throughput analysis of liquid samples with significant applications in biomedicine and biochemistry. Nevertheless, extracting content-rich information from single picolitre-sized droplets at high throughputs remains challenging due to the weak signals associated with these small volumes. Overcoming this limitation would be transformative for fields that rely on high-throughput screening, enabling broader multiparametric analysis.
View Article and Find Full Text PDFPreparation and pharmacokinetic evaluation of a sertraline-methylpropyphenazone prodrug: a comparative metabolic study on the plasma and brain tissues of rats using LC-MS/MS analysis.
RSC Adv
January 2025
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University P.O. Box 80260 Jeddah 21589 Saudi Arabia +966 553399718.
A mutual prodrug of sertraline-methylpropyphenazone (SER-MP) was prepared and characterized using a spectral method. The yield of the prepared SER-MP was 90%, and its purity reached 98.8%.
View Article and Find Full Text PDFUltrashort pulse sources are complex and resource-intensive. To reduce overhead and simplify operations, we had previously developed a method to deliver ultra-short pulses through fiber-optic links to multiple locations and to characterize them remotely using a compact detector module. We created a pulse pair with varying delays at the central location using a pulse shaper before launching them into the fiber links and measured the first and second-order autocorrelations at the satellite location.
View Article and Find Full Text PDFWe developed a scanning dual-comb spectroscopic microscopy (S-DCSM) system to acquire multidimensional optical information of transparent or semi-transparent samples. The system demonstrated the capability to perform spectral imaging of absorbance, optical phase, optical thickness, linear dichroism, and birefringence within the spectral range covered by optical frequency combs (OFCs). The spatial distribution of optical thickness in HeLa cells was measured as 8.
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