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Synergistic Enhancement of Ligand & Cluster Connectivity to Construct Highly Stable Fluorescein-Based MOFs with Thickened Channel Walls for Boosting Photocatalytic Activity.

Small

January 2025

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal, University Xuzhou, Jiangsu, 221116, P. R. China.

Fabricating visible-light-responsive metal-organic frameworks (MOFs) with high stability and effective catalytic functionality remains a long-term pursuit yet a great challenge. Herein, a strategy of increasing ligand and cluster connectivity is developed to construct highly stable fluorescein MOFs, La-CFL, presenting a new (4,8)-connected topological structure compared to Cd-FL constructed using 6-connected dinuclear clusters and 3-connected tritopic ligands. La(CFL) containers like Chinese "Ritual Wine Vessels (Jue)" resemble linear arrangements interconnected by the [La(COO)] clusters.

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Retrospective analysis of disease characteristics and treatment patterns among patients with esophageal cancer across 14 surgically represented centers.

Cancer Biol Med

January 2025

State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China.

Objective: Esophageal cancer (EC) ranks eighth among cancers in cancer-related deaths globally, and ~44% of new cases occur in China. We sought to describe the clinical characteristics and treatment landscape of EC in China before the approval of immunotherapy in 2020.

Methods: CHANNEL was a large, retrospective study using patient-level data from 14 hospitals/cancer centers across China, including adults initiating therapy for newly diagnosed EC (January to December 2018).

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Lifecycle of an introduced (Bucephalidae) trematode in the Tone River system, Japan.

J Helminthol

January 2025

Toho University, Faculty of Science, 2-2-1 Miyama, Funabashi, Chiba274-8510, Japan.

During 2021 through 2023, the golden mussel and freshwater fishes were sampled from 28 sites in the Tone River system, Japan, and adult trematodes of were found in the fishes. Molecular and morphological analyses based on 28S rDNA and the ITS1-5.8S-ITS2 region revealed the trematode as '', previously reported in Mainland China and likely introduced to Japan.

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Purpose of this study is to investigate the quality and reliability of YouTube video contents on prophylactic mastectomy. The search terms "prophylactic mastectomy," "prophylactic mastectomy surgery," "preventive surgery for breast cancer," "risk-reducing mastectomy," and "prophylactic mastectomy and breast reconstruction" were searched on YouTube. The uploader, video content, length (seconds), upload date, number of days since upload date, number of views, number of comments, and likes were recorded and evaluated.

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Chitinase 1 (CHIT1), as a chitin-specific hydrolase, significantly influences the progression of Alzheimer's disease (AD) through microglia-associated inflammation and amyloid beta (Aβ) plaque accumulation. However, the precise mechanism of CHIT1 action in AD remains uncertain. The effects of CHIT1 on cerebral blood flow (CBF), hippocampal volume, and cognitive function were investigated in APP/PS1 mice.

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