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Molecular diagnosis of an unusual aetiology of chronic abdominal pain with ascites.
BMJ Case Rep
August 2024
Division of Infectious Disease, Albert Einstein College of Medicine, Bronx, NY, USA.
Article Synopsis
- An immigrant woman in her 60s presented with abdominal pain, bloating, early satiety, and weight loss, leading to a complex series of medical evaluations.
- Diagnostic tests revealed non-caseating granulomatous endometritis in her thickened endometrial tissue, but cultures were initially negative for TB.
- After finding urine mycobacterial cultures positive for pansusceptible MTB, she was treated with a combination of antibiotics, resulting in significant improvement in her symptoms.
Revolutionizing chronic endometritis diagnosis: real-time polymerase chain reaction unveils microbial pathogens in Indian women with abnormal bleeding and reproductive challenges.
AJOG Glob Rep
August 2024
LifeCell International (P) Ltd. (Nandagopal, Rajan N., Padhiar, Abhaya, and Ghambir), Chennai, Tamil Nadu, India.
Background: This study aimed to assess the utility of real-time-polymerase chain reaction (PCR) for diagnosing chronic endometritis (CE) by targeting 11 prevalent pathogens and to compare the outcomes with conventional culture-based diagnosis.
Study Design: A retrospective analysis was conducted on 500 patients with clinical conditions such as abnormal bleeding, in vitro fertilization failure, recurrent implantation failure, recurrent miscarriage, and recurrent pregnancy loss. The prevalence of 11 key pathogens associated with CE was evaluated in endometrial biopsy samples.
Histopathologic patterns of female genital tuberculosis with clinical correlation: a 10-year (2013-2022) retrospective cross-sectional study.
BMC Womens Health
June 2024
Department of Gynecology, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Article Synopsis
- Female genital tuberculosis (FGTB) often goes undiagnosed and can cause infertility, prompting this study to explore its locations, patterns, and relation to symptoms and acid-fast bacilli (AFB) findings.
- Conducted at Tikur Anbessa Specialized Hospital, the study examined 122 patients with FGTB from 2013 to 2022, revealing that 0.94% of gynecological samples showed FGTB, primarily in the endometrium, with symptoms including menstrual disturbances and pain.
- The findings suggested that FGTB should be considered in reproductive-age women with specific symptoms, highlighting the endometrium's common involvement and noting that early-stage granulomas were prevalent, with a notable presence
Morbidity During the Early Interwar Period (1923-27): A Historical-Epidemiological Study of 15,146 Cases Treated at the "Agios Dimitrios" Hospital in Thessaloniki, Greece.
Cureus
October 2023
Clinic of Social and Family Medicine, Medical School, University of Crete, Heraklion, GRC.
Background and objective The period spanning 1923-1927 was a turbulent period in Greek history following the catastrophic defeat of the Greek army in September 1922, known as the "Asia Minor Catastrophe". The massive settlement of refugees in Thessaloniki, Greece, entailed massive economic, public health, and social challenges. The present historical-epidemiological study aims to evaluate the diseases of individuals hospitalized at the "Agios Dimitrios" Hospital in Thessaloniki during the aforementioned period.
View Article and Find Full Text PDFIntroduction Endometrial aspiration cytology (EAC) is a noninvasive, rapid, and cost-effective procedure for diagnosing gynecological disorders. This study aimed to validate endometrial aspiration as a routine, safe, and efficient outpatient diagnostic procedure, correlating its findings with histopathology evaluations to facilitate early surgical planning for patients with abnormal uterine bleeding. Materials and methods This cross-sectional study involved patients of reproductive, menopausal, and postmenopausal age groups who presented with diverse gynecological concerns that required dilatation and curettage.
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