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Impact of fluconazole on outcomes of patients with primary pulmonary coccidioidomycosis: a commercial health insurance claims-based, propensity score matched analysis.
Clin Infect Dis
January 2025
Department of Medicine, Division of Infectious Diseases, and the Department of Medical Microbiology and Immunology, University of California, Davis, Sacramento, California, USA.
Background: Patients with pulmonary coccidioidomycosis often experience prolonged symptoms lasting weeks to months. Limited data exist regarding whether fluconazole prevents development of disseminated disease or shortens symptom duration. We describe factors associated with fluconazole receipt and assess its effect on outcomes among patients with pulmonary coccidioidomycosis.
View Article and Find Full Text PDFTuberculous Subclavian Artery Pseudoaneurysm in a Young Male With Hemoptysis.
Cureus
December 2024
Vascular Surgery, Unidade Local de Saúde São José, Lisbon, PRT.
Subclavian artery pseudoaneurysms (SAPs) are rare and most often secondary to trauma. On the contrary, a mycotic origin is exceedingly rare, and defining this etiology can become challenging. We present a rare case of a tuberculous SAP in a young patient.
View Article and Find Full Text PDFPredictors of Cryptococcus gattii clinical presentation and outcome: An international study.
Clin Infect Dis
January 2025
Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Background: Infection by Cryptococcus gattii can lead to pulmonary or central nervous system (CNS) disease, or both. Whether site of infection and disease severity are associated with C. gattii species and lineages or with certain underlying medical conditions, or both is unclear.
View Article and Find Full Text PDFEpidemiological and clinical features of a large blastomycosis outbreak at a paper mill in Michigan.
Clin Infect Dis
October 2024
Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Article Synopsis
- A significant outbreak of blastomycosis, a serious fungal infection, occurred among workers at a paper mill in Delta County, Michigan, affecting 131 patients from December 2022 to July 2023.
- Hospitalization rates were notable, with 12% requiring hospitalization, and factors like diabetes and elevated urine antigen levels were linked to more severe cases.
- This outbreak is the largest recorded in the U.S., highlighting the importance of early diagnosis to avoid unnecessary antibiotic use and improve treatment outcomes.
Late Relapse of Previous Pulmonary Cryptococcosis With Symptoms Resembling Cerebral Infarction: A Case Report.
Case Rep Infect Dis
October 2024
Department of Neurosurgery, Otto-Von-Guericke-University Magdeburg, Magdeburg, Germany.
Cryptococcosis, an infection caused by , predominantly targets the central nervous system (CNS) in patients with AIDS but is not limited to this group. The disease can also occur in individuals with various immunosuppressive conditions, frequently involving the brain or lungs. Cryptococcal meningitis (CM) is the most common form of fungal meningoencephalitis, leading to intracerebral infections, cerebral infarction, or hydrocephalus.
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