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Development and validation of a novel 7α-hydroxy-4-cholesten-3-one (C4) liquid chromatography tandem mass spectrometry method and its utility to assess pre-analytical stability.
Clin Chem Lab Med
January 2025
Department of Clinical Biochemistry, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Wythenshawe, UK.
Objectives: 7α-Hydroxy-4-cholesten-3-one (C4) is the common intermediary of both primary bile acids. C4 is recommended by the British Society of Gastroenterology for the investigation of bile acid diarrhoea (BAD) in patients with chronic diarrhoea. This project aimed to develop and validate an assay to quantitate C4 in serum and assess the stability of C4 in unseparated blood.
View Article and Find Full Text PDFManufacturing of PEEK orthodontic baseplate and 3D-printed alloy components from an intraoral scan.
Medicine (Baltimore)
April 2024
Department of Pharmacy Practice and Pharmacotherapeutics, University of Sharjah, Sharjah, United Arab Emirates.
This paper demonstrates a digital manufacturing technique of a removable orthodontic appliance from an intraoral scan. An intraoral scan was made for the maxillary and mandibular arches. 3Shape Orthodontics Appliance Designer produced the virtual Hawley retainer, consisting of alloy components (Adam Clasps and Fitted Labial bow) and a base plate.
View Article and Find Full Text PDFMultiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes.
Curr Biol
January 2024
Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, MO 66160, USA. Electronic address:
Although Lepidopteran females build a synaptonemal complex (SC) in pachytene, homologs do not crossover, necessitating an alternative method of homolog conjunction. In Bombyx mori oocytes, the SC breaks down at the end of pachytene, and homolog associations are maintained by a large oocyte-specific structure, which we call the bivalent bridge (BB), connecting paired homologs. The BB is derived from at least some components of the SC lateral elements (LEs).
View Article and Find Full Text PDF[Miniscrews during the retention phase: indications, therapeutic means and effects].
Orthod Fr
September 2021
Département d'Orthopédie Dento-Faciale, Faculté d'Odontologie, rue Guillaume Paradin, 69372 Lyon cedex 08, France, Unité Fonctionnelle d'Orthopédie Dento-Faciale, Centre de Traitements Dentaires, Hospices Civils de Lyon, 6-8 place Depéret, 69365 Lyon cedex 03, France.
Even if miniscrews are mainly used in the active phase, their uses during the contention have been reported for a few years either by installation of miniscrews de novo or by taking advantage of miniscrews inserted during the active phase. The objective of this article is to describe the uses - reported in the literature - of miniscrews during the retention phase. We have conducted a research from the database PubMed with keywords associations.
View Article and Find Full Text PDFThe lateral arm device for mammographic breast procedures: overview of its uses, safety, and efficacy.
Expert Rev Med Devices
May 2021
Division of Surgical Oncology, Department of Surgery, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH, USA.
: Percutaneous image-guided biopsy is the procedure of choice for diagnosing suspicious abnormalities on breast imaging. Stereotactic, ultrasound, and magnetic resonance imaging are used for image-guided breast biopsies. Stereotactic guidance uses mammography to localize lesions and facilitate placement of a core biopsy needle.
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