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Bone Marrow Niche in Cardiometabolic Disease: Mechanisms and Therapeutic Potential.
Circ Res
January 2025
Division of Cardiovascular Medicine, Department of Medicine (J.B.H., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.
Cardiovascular and cardiometabolic diseases are leading causes of morbidity and mortality worldwide, driven in part by chronic inflammation. Emerging research suggests that the bone marrow microenvironment, or marrow niche, plays a critical role in both immune system regulation and disease progression. The bone marrow niche is essential for maintaining hematopoietic stem cells (HSCs) and orchestrating hematopoiesis.
View Article and Find Full Text PDFA cross-sectional study on the assessment of adherence to cardiovascular medications in Sudan heart center.
PLoS One
January 2025
Ambulatory Healthcare Services, Academic Affairs, Abu Dhabi Health Services (SEHA), Abu Dhabi, UAE.
Background: Non-adherence to cardiovascular medications is a global problem with clinical, economic, and humanistic consequences. Investigation of this problem may open the road for proper management of cardiovascular diseases.
Objective: Our objectives were to assess the level of adherence to, and to examine factors influencing adherence to, cardiovascular medications in subjects visiting a heart center in Sudan.
High pulse pressure is associated with an increased risk of prediabetes in hypertensive individuals: A retrospective study based on an adult Chinese population.
PLoS One
January 2025
Department of Emergency, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Objectives: The pulse pressure (PP) is an important factor influencing the outcomes of diabetes. However, the relationship between the PP and prediabetes has been rarely studied and how this association might be impacted by hypertension is not clear.
Methods: In this study, we retrospectively included 184,252 adults from 32 regions in China, spanning from 2010 to 2016.
Genetic influence on choroidal vascularity index.
PLoS One
January 2025
Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Purpose: To investigate the heritability of genetic influence on macular choroidal vascularity index (CVI).
Methods: Total choroidal area (TCA), luminal area (LA), and CVI was measured using horizontal scan of spectral-domain optical coherence tomography with enhanced depth imaging in the 373 healthy twin participants. Characteristics of the participants were investigated, including age, sex, axial length, hypertension, diabetes, drinking habits, and smoking status.
Video-based estimation of blood pressure.
PLoS One
January 2025
Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, United States of America.
In this work, we propose a non-contact video-based approach that estimates an individual's blood pressure. The estimation of blood pressure is critical for monitoring hypertension and cardiovascular diseases such as coronary artery disease or stroke. Estimation of blood pressure is typically achieved using contact-based devices which apply pressure on the arm through a cuff.
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