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Peptoniphilus vaginalis bacteremia in a patient with diabetic foot infection: First reported case and literature review.
Diagn Microbiol Infect Dis
March 2025
Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address:
Background: Peptoniphilus vaginalis, a Gram-positive anaerobic coccus, is a recently characterized species within the Peptoniphilus genus. No studies have detailed its features. This report documents the first case of P.
View Article and Find Full Text PDFHigh Resolution Mass Spectrometry Fragmentation Rules of Etomidate and Its Structural Analogues.
Fa Yi Xue Za Zhi
December 2024
Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.
Objectives: To explore the characteristic fragment ions, ion abundance ratios and mass spectrometry fragmentation rules of etomidate and its structural analogues by using gas chromatography-quadrupole/orbitrap mass spectrometry (GC-Q/Orbitrap MS) and liquid chromatography-linear ion trap quadrupole-orbitrap mass spectrometry (LC-LTQ-Orbitrap MS) techniques, providing important data support for the identification and prediction of etomidate structural analogues.
Methods: GC-Q/Orbitrap MS and LC-LTQ-Orbitrap MS were used to analyze metomidate, etomidate, isopropoxate and propoxate, to obtain their GC high resolution mass spectra and LC high resolution mass spectra.
Results: Under the electron impact (EI) ion source mode, etomidate, metomidate and the other two analogues all produced their molecular ions and seven identical fragment ions ( 77.
Patient-Directed Discharge in Hand Infection Cases: Interactions Between Intravenous Drug Use, Socioeconomic Factors, and Subsequent Readmissions.
Ann Plast Surg
March 2025
Division of Plastic and Reconstructive Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Background: Patient-directed discharge (PDD) poses a significant challenge in healthcare. Prior studies have shown associations of PDD with factors like race, housing, psychiatric illness, socioeconomic status, and intravenous drug use (IVDU). This study aims to identify factors contributing to PDD in hand infection patients at a public safety-net hospital and to investigate the long-term consequences through readmissions or returns to the emergency department (ED).
View Article and Find Full Text PDFPostoperative nutritional support after pancreaticoduodenectomy in adults.
Cochrane Database Syst Rev
March 2025
Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Background: Resection of the head of the pancreas is most commonly done by a pancreaticoduodenectomy, known as a Whipple procedure. The most common indication for pancreaticoduodenectomy is malignancy, but can include benign tumours and chronic pancreatitis. Complete surgical resection, with negative margins, provides the best prospect of long-term survival.
View Article and Find Full Text PDFA Rare Guillain-Barré Syndrome Variant with Multi-Ganglioside Reactivity: A Case of Severe Cranial Nerve Involvement.
Rev Neurol
February 2025
Neuromuscular Diseases Unit, Neurology Department, University Hospital Vall d'Hebron, 08035 Barcelona, Spain.
Introduction: We present a rare case of acute immune-mediated polyradiculoneuritis, a Guillain-Barré Syndrome (GBS) variant, manifesting as ophthalmoparesis-ataxia, facial diplegia, and acute bulbar palsy, accompanied by a unique autoimmune profile.
Clinical Case: A 75-year-old female developed rapidly progressive symptoms, including bilateral non-reactive mydriasis, ptosis, complete ophthalmoplegia, bilateral facial weakness, tongue immobility, palatal paralysis, limb dysmetria, ataxia, and brisk generalized tendon reflexes, all while maintaining a preserved mental state. Symptoms emerged 10 days after a probable gastrointestinal infection.
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