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Optimization of erythritol production through fermentation using molasses as carbon source.
Acta Biochim Pol
January 2025
Department of Biotechnology, Indonesia International Institute for Life Sciences, East Jakarta, Indonesia.
Erythritol is a beneficial sugar alcohol that can be used as a sugar substitute for diabetic patients. Erythritol is a bioproduct produced by microorganisms as a response to high osmotic pressure and stress in the growth medium. High concentrations of carbon source substrate can increase the osmotic pressure and provide more nutrient supply for yeast growth and metabolism.
View Article and Find Full Text PDFFlow environment affects nutrient transport in soft plant roots.
Soft Matter
January 2025
Microfluidics and Microscale Transport Processes Laboratory, Department of Mechanical Engineering, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India.
This work estimates Michaelis-Menten kinetics parameters for nutrient transport under varying flow rates in the soft roots of Indian mustard () using a plant fluidic device. To find the metallic components within the roots, inductively coupled plasma mass spectrometry (ICP-MS) analysis was performed. The flow rate-dependent metabolic changes were examined using Raman spectral analysis.
View Article and Find Full Text PDFFinite element models of intervertebral disc: recent advances and prospects.
Ann Med
December 2025
Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, The People's Republic of China.
Objectives: The incidence rate of intervertebral disc degeneration (IVDD) is increasing year by year, which brings great harm to our health. The change of biomechanical factors is an important reason for IVDD. Therefore, more and more studies use finite element (FE) models to analyze the biomechanics of spine.
View Article and Find Full Text PDFPhosphorus-solubilizing fungi promote the growth of P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system-related gene expression.
Front Genet
January 2025
Chongqing Engineering Laboratory of Green Planting and Deep Processing of Famous-Region Drug in the Three Gorges Reservoir Region, College of Biology and Food Engineering, Chongqing Three Gorges University, Chongqing, China.
Introduction: P. Y. Li is a plant used to treat respiratory diseases such as pneumonia, bronchitis, and influenza.
View Article and Find Full Text PDFHyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium.
Ocul Surf
January 2025
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Zhejiang, 325000, China; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University, Zhejiang, 325000, China. Electronic address:
Unlabelled: The activation of the NLRP3 inflammasome by hyperosmotic stress is a critical pathophysiological response in dry eye disease (DED), driving the chronic cycle of inflammation on the ocular surface. The specific mechanism underlying hyperosmotic mechanical stimulation activates the NLRP3 inflammasome remains unclear. This study provides evidence that PIEZO1, a mechanosensitive ion channel, functions as the primary receptor for corneal epithelial cells in sensing mechanical stimulation induced by tear hyperosmolarity.
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