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The natural history of cytologically low-risk indeterminate thyroid nodules.
J Clin Endocrinol Metab
January 2025
Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy.
Background: Thyroid nodules classified cytologically as low-risk indeterminate lesions (TIR3A) on fine-needle aspiration biopsy (FNAB) present a clinical challenge due to their uncertain malignancy risk. This single-center study aimed to evaluate the natural history of TIR3A nodules.
Materials And Methods: FNABs performed between July 2017 and December 2019 were retrospectively retrieved and patients with TIR3A nodules were evaluated at baseline and throughout a follow-up based on ultrasound (US) parameters and clinical data.
Recalibrating Protection Factors Using Millisecond Hydrogen/Deuterium Exchange Mass Spectrometry.
Anal Chem
January 2025
School of Molecular and Cellular Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U.K.
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a powerful technique to interrogate protein structure and dynamics. With the ability to study almost any protein without a size limit, including intrinsically disordered ones, HDX-MS has shown fast growing importance as a complement to structural elucidation techniques. Current experiments compare two or more related conditions (sequences, interaction partners, excipients, conformational states, etc.
View Article and Find Full Text PDFEfficient Double-Layer Evaporators with Adjustable Pores for Sustainable Solar Evaporation.
Langmuir
January 2025
Ningbo Key Lab of Polymer Materials, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 315211 Ningbo, P. R. China.
Solar-driven desalination technology is currently an important way to obtain freshwater resources. Significantly, porous materials are used as substrate materials of interface solar evaporator, and their specific impact of water transport property and thermal management during evaporation is worth exploring. In this paper, poly(vinyl alcohol) (PVA) sponges were prepared by a chemical foaming method, adjusted the PVA polymerization degree, and formaldehyde-hydroxyl ratio to regulate the pore size, and polypyrrole (PPy) was grown in situ on the surface skeleton of PVA sponge to construct a new interfacial solar evaporator (PPy/PVA) with different pore structures.
View Article and Find Full Text PDFMolecularly imprinted hydrogels embedded with two-dimensional photonic crystals for the detection of dexamethasone/betamethasone sodium phosphate.
Mikrochim Acta
January 2025
Key Laboratory of New Energy & New Functional Materials, Shaanxi Key Laboratory of Chemical Reaction Engineering, College of Chemistry and Chemical Engineering, School of Medicine, Yan'an University, Yan'an, Shaanxi, 716000, People's Republic of China.
Dexamethasone sodium phosphate (DSP) and betamethasone sodium phosphate (BSP) imprinted hydrogels embedded with two-dimensional photonic crystals (2DPC) were developed as hormones-sensitive photonic hydrogel sensors with highly sensitive, selective, anti-interference and reproducible recognition capability. The DSP/BSP molecularly imprinted photonic hydrogels (denoted as DSP-MIPH and BSP-MIPH) can specifically recognize DSP/BSP by rebinding the DSP/BET molecules to nanocavities in the hydrogel network. This recognition is enabled by the similar shape, size, and binding sites of the nanocavities to the target molecules.
View Article and Find Full Text PDFFamily Size across the Life Course and Cognitive Decline in Older Mexican Adults.
J Gerontol B Psychol Sci Soc Sci
January 2025
College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Objectives: A growing body of research has identified associations between family size and cognition in older adults. These studies largely focus on older adults' own fertility history instead of sibship size, defined as one's number of siblings. Sibship size may impact cognitive development during early childhood, creating differences that may persist into late-life.
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