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Pulpitis is an important and prevalent disease within the oral cavity. Thus, animal models are necessary tools for basic research focused on pulpitis. Researchers worldwide often use dogs and miniature pigs to construct animal models of pulpitis.

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Droplet evaporation on solid substrates is a ubiquitous phenomenon and is relevant in many natural and industrial processes. Whereas it has been reported that the evaporation process is sped up on soft substrates compared with that on hard substrates, no attempt has been made in exploring how substrate stretching affects droplet evaporation and evaporative deposition patterns. Here, we systematically investigate the contact line dynamics of droplets evaporating on substrates with different stiffnesses and stretching ratios and the structures of the evaporative deposition patterns of nanoparticles.

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Tissue selective ultrasonic debridement is a new method of debriding chronic wounds that prepares the wound for advanced tissue application. This article presents the case of an 89-year-old woman with a chronic nonhealing wound to her lateral distal leg. The wound had a significant amount of biofilm and fibrous slough.

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Fully guided system for position-predictable autotransplantation of teeth: A randomized clinical trial.

Int Endod J

January 2025

Department of Oral and Maxillofacial Surgery, Guangdong Engineering Research Center of Oral Restoration and Reconstruction Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.

Aim: Autotransplantation of teeth (ATT) is a viable biological method for addressing dental defects. The objective was to achieve occlusal reconstruction-orientated ATT to enhance functionality and obtain optimal location and adjacency. This study proposes a new concept of a guide (a fully guided system) to achieve position-predictable ATT.

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Unexpected amine-triggered skeletal modification of fascaplysin and its derivatives: rapid access to δ,γ-biscarbolines.

Org Biomol Chem

January 2025

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Guizhou Medical University, Guiyang 550014, China.

An unsuccessful attempt to directly construct alkaloid iheyamine A from a fascaplysin framework resulted in the discovery of a novel synthetic approach to alkylated δ,γ-biscarboline derivatives. With the easy-to-operate reaction conditions of this protocol, 18 alkylated biscarbolines have been prepared in moderate to good yields. An unexpected domino transformation was proposed to involve a pyridinium ring-opening/aza-electrocyclization/oxidative deformylation sequence.

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