An antibody to rat lysozyme has been prepared and its activity and specificity studied by inhibition and double diffusion techniques. By means of this antibody together with fluorescent anti-rabbit globulin, the distribution of lysozyme in rat and mouse polymorphs and macrophages has been examined and some changes which follow phagocytosis demonstrated.
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Spinal Cord
January 2025
McKnight Brain Institute, University of Florida, Gainesville, FL, USA.
Study Design: Experimental Animal Study.
Objective: To continue validating an antibody which targets an epitope of neurofilament light chain (NF-L) only available during neurodegeneration and to utilize the antibody to describe the pattern of axonal degeneration 10 days post-unilateral C4 contusion in the rat.
Setting: University of Florida laboratory in Gainesville, USA.
Biomaterials
December 2024
Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon Based Functional Materials & Devices, Soochow University, Suzhou, 215123, China. Electronic address:
The development of novel microspheres for the combination of sonodynamic therapy (SDT) with transarterial embolization (TAE) therapy to amplify their efficacy has received increasing attention. Herein, a novel strategy for encapsulating sonosensitizers (e.g.
View Article and Find Full Text PDFProg Orthod
January 2025
Institute for Innovation in Digital Healthcare (IIDH), Yonsei University Health System, Seoul, Korea.
J Affect Disord
December 2024
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, USA.
Experimental studies of major depressive disorder (MDD) and stress reveal connectivity disturbances of the prefrontal cortex (PFC) that may involve molecular and morphological changes in myelin and the axons it enwraps. These alterations may also affect the nodes of Ranvier (NR), myelin-bare axon stretches along myelin sheaths necessary for action potential propagation, as well as the paranodes, specialized regions of the myelin sheath flanking NRs. Thus, we investigated whether paranode length and the labeling of paranode marker CASPR in PFC white matter (WM) differed in MDD subjects and chronic stress-exposed rats, as compared to their respective controls.
View Article and Find Full Text PDFMicrosyst Nanoeng
December 2024
Research Center for Bionic Sensing and Intelligence, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 518055, Shenzhen, China.
We present a versatile platform for label-free magnetic separation of plasma, tailored to accommodate diverse environments. This innovative device utilizes an advanced long-short alternating double Halbach magnetic array, specifically engineered for optimal magnetic separation. The array's adaptability allows for seamless integration with separation channels of varying sizes, enabling static separation of whole blood.
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