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Integrating Retinal Segmentation Metrics with Machine Learning for Predictions from Mouse SD-OCT Scans.
Curr Eye Res
January 2025
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Purpose: This study aimed to initially test whether machine learning approaches could categorically predict two simple biological features, mouse age and mouse species, using the retinal segmentation metrics.
Methods: The retinal layer thickness data obtained from C57BL/6 and DBA/2J mice were processed for machine learning after segmenting mouse retinal SD-OCT scans. Twenty-two models were trained to predict the mouse groups.
Stromal PDGFR-beta expression is a prognostic factor in high-grade serous ovarian cancer patients but is it also predictive for response to antiangiogenic treatment?
J Cancer Res Clin Oncol
January 2025
Department of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Objective: In advanced ovarian cancer, the majority of patients receive anti-angiogenic treatment with bevacizumab. However, its use is often associated with severe side effects, and not all patients benefit from the therapy. Currently, there are no reliable biomarkers to predict response to treatment.
View Article and Find Full Text PDFOncocytoma: a rare neoplasm of the caruncle.
BMJ Case Rep
January 2025
Ophthalmology, Madigan Army Medical Center, Tacoma, Washington, USA.
Oncocytoma is a rare benign neoplasm of the glandular tissue, most commonly found in the caruncle of the eye. These lesions have an excellent prognosis and have not been reported to recur after resection from the caruncle. Given the wide range of differentials and potential for malignancy, excision and histopathological examination are recommended to establish the diagnosis and guide proper treatment.
View Article and Find Full Text PDFSuccessfully enucleation of a rare pancreatic schwannoma: A case report.
Int J Surg Case Rep
January 2025
Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia.
Introduction And Importance: Pancreatic schwannoma (PS) is an extremely rare benign tumor also known as neurilemoma or neuroma. The majority of PS develop cystic lesions, and its preoperative diagnosis is challenging due to its tendency to mimic other lesions of the pancreas. Herein, we reported a case of body PS incidentally discovered in an 81-year-old male, which was successfully treated through enucleation.
View Article and Find Full Text PDFA rare journey of a thymoma: A case report.
Int J Surg Case Rep
January 2025
Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital, Nepal.
Introduction And Importance: Thymoma is the most common primary anterior mediastinal tumor in adults. Invasive thymomas infiltrate organs adjacent to the mediastinal pleura, including the lungs, great vessels, heart, pericardium, and diaphragm. Complete resection of invasive thymoma leads to a better prognosis.
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