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Chronic idiopathic urticaria: infiltrating cells and related cytokines in autologous serum-induced wheals.
Clin Immunol
March 2005
II Department of Dermatological Sciences, University of Florence, Via degli Alfani, 37, 50121 Florence Italy.
The term chronic autoimmune urticaria (CAIU) is used for chronic urticaria in subjects who present a whealing response to the intradermal injection of autologous serum, suggesting the presence of pathogenic antibody activities. In this study, we examined 28 chronic urticaria subjects with positive autologous serum skin test (ASST), all of whom presented autologous serum-induced lesions at different evolutive stages. Punch biopsies were taken from lesional skin of six subjects at 10', eight subjects at 30', six subjects at 60', and four subjects each at 24 and 48 h.
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