AI Article Synopsis
- The study investigated how aminoguanidine reacts with various sugar-derived compounds at a specific temperature and pH level.
- For two of the compounds (1a and 1b), two main reaction products were identified as 3-amino-1,2,4-triazine derivatives, with consistent product ratios regardless of reagent amounts or mixing order.
- In contrast, the other compounds (1c and 1d) only produced one type of product (the 5-substituted triazine derivatives), and no hydrazone or bishydrazone formations were detected.
Article Abstract
The reactions of aminoguanidine (guanylhydrazine) with 3-deoxy-D-erythro-hexos-2-ulose (1a), 3-deoxy-D-glycero-pentose-2-ulose (1b), D-erythro-hexos-2-ulose (1c), and D-glycero-pentose-2-ulose (1d) were examined at 37 degrees at a solution pH of 7.0 (phosphate buffer). For 1a and 1b, two major products were observed and shown respectively to be the 5- and 6-substituted 3-amino-1,2,4-triazine derivatives. The ratios of the products were independent of the amount of aminoguanidine present or the order of mixing the reagents prior to the experiments. For 1c and 1d, only the 5-substituted triazine derivatives were formed. No evidence for hydrazone or bishydrazone formation was observed.
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| http://dx.doi.org/10.1016/s0008-6215(00)90999-6 | DOI Listing |
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