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Testing syndemic models along pathways to psychotic spectrum disorder: implications for population-level preventive interventions.
Psychol Med
March 2025
Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Background: Population-level preventive interventions are urgently needed and may be effective for psychosis due to social determinants. We tested three syndemic models along pathways from childhood adversity (CA) to psychotic spectrum disorder (PSD) and their implications for prevention.
Methods: Cross-sectional data from 7461 British men surveyed in 5 population subgroups.
Differential expression of plasma extracellular vesicles microRNAs and exploration of their association with bone metabolism in childhood trauma participants treated in a psychosomatic clinic.
Front Endocrinol (Lausanne)
March 2025
Medical Sociology and Psychobiology, University of Potsdam, Potsdam, Germany.
Introduction: Early life stress (ELS) impacts neurotransmitters and cell communication, potentially disrupting neurological and physiological processes. Recently, ELS has been implicated in impaired bone metabolism, with extracellular vesicles (EVs) and their cargo, microRNAs (miRNAs), might affecting this process. This research aimed to elucidate the association between childhood trauma, a specific form of ELS, and bone metabolism through studying miRNA in EVs within three steps: firstly, examining alterations of EV miRNAs between ELS and controls, secondly analyzing associations between altered EV miRNAs and bone markers, and thirdly exploring the target gene prediction and enrichment pathways of altered EV miRNAs.
View Article and Find Full Text PDFUrban Spillover, Health Disparities, and Community Strengths in Small Towns in Central Texas.
Healthcare (Basel)
February 2025
UT School of Public Health San Antonio, UT Health San Antonio, San Antonio, TX 78229, USA.
: Small-town residents face healthcare inequities that result in poorer outcomes compared to those living in urban areas. These disparities are deeply rooted in socioeconomic and demographic factors as well as in access to healthcare services. This study aimed to explore health disparities and community strengths within small towns in Williamson County, Central Texas, intensified by urban spillover.
View Article and Find Full Text PDFThe lived experiences of intimate partner violence in Iranian women staying with their abusive partners.
BMC Womens Health
March 2025
Department of Counseling, Faculty of Psychology and Education, Allameh Tabatabai University, Tehran, Iran.
Background: Intimate partner violence (IPV) has severe physical and mental complications; however, some women stay in abusive relationships. There is little in-depth qualitative work on the experiences of IPV in Iranian women staying with their abusive partners. In this study, we aim to explore the lived experiences of IPV in Iranian women with a history of remaining in abusive relationships in order to help identify the factors related to their decision to stay with their abusive partners.
View Article and Find Full Text PDFRelationship between workplace violence and occupational health in emergency nurses: The mediating role of dyssomnia.
Nurs Crit Care
March 2025
Department of Emergency Medicine, West China Hospital, Sichuan University, West China School of Nursing, Sichuan University, Chengdu, China.
Background: Violence in the workplace is a common concern within the health care field, particularly in the high-intensity, high-risk and high-stress environment of the emergency and critical care department. Workplace violence poses significant risks to their physical, psychological and sleep quality. Therefore, it is essential to explore the mechanisms through which workplace violence impacts the occupational health of emergency and critical care nurses.
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