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Cross-Sectional Association Between Left Ventricular Geometric Patterns, Cortical Cerebral Microinfarcts, and Cognition.
J Am Heart Assoc
January 2025
Background: Left ventricular (LV) geometric patterns are associated with cognitive impairment and cerebral small vessel disease. As a novel magnetic resonance imaging marker of cerebral small vessel disease and a risk factor for cognitive dysfunction, cortical cerebral microinfarcts (CMIs) have been associated with heart disease through mechanisms including cardioembolism and cerebral hypoperfusion. Further investigation is required to determine whether cortical CMIs could arise from hemodynamic changes related to LV geometry, thus elucidating the connection between LV geometry and cognitive function.
View Article and Find Full Text PDFNon-dominant handgrip strength is associated with higher cardiorespiratory endurance and elevated NT-proBNP concentrations in ambulatory male adult outpatients with stable HFrEF.
Narra J
December 2024
Department of Cardiology and Vascular Medicine, Harapan Kita Hospital, Jakarta, Indonesia.
Understanding the significance of handgrip strength is essential for identifying frailty in heart failure patients. The aim of this study was to identify the association between handgrip strength and cardiorespiratory endurance while highlighting the importance of the musculoskeletal system in cardiac rehabilitation for patients with heart failure. An observational cross-sectional study was conducted at Harapan Kita Hospital, Jakarta, Indonesia, from April 2022 to April 2023, among patients with heart failure with reduced ejection fraction (HFrEF) attributed to cardiomyopathy or coronary artery disease.
View Article and Find Full Text PDFGeneration of high-resolution MPRAGE-like images from 3D head MRI localizer (AutoAlign Head) images using a deep learning-based model.
Jpn J Radiol
January 2025
Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-Cho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Purpose: Magnetization prepared rapid gradient echo (MPRAGE) is a useful three-dimensional (3D) T1-weighted sequence, but is not a priority in routine brain examinations. We hypothesized that converting 3D MRI localizer (AutoAlign Head) images to MPRAGE-like images with deep learning (DL) would be beneficial for diagnosing and researching dementia and neurodegenerative diseases. We aimed to establish and evaluate a DL-based model for generating MPRAGE-like images from MRI localizers.
View Article and Find Full Text PDFImpact of Subarachnoid Hemorrhage on Human Glymphatic Function: A Time-Evolution Magnetic Resonance Imaging Study.
Stroke
January 2025
Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Norway (P.K.E., A.L., P.A.R., A.G.S., L.M.V.).
Background: Subarachnoid hemorrhage (SAH) is associated with significant mortality and morbidity. The impact of SAH on human glymphatic function remains unknown.
Methods: This prospective, controlled study investigated whether human glymphatic function is altered after SAH, how it differs over time, and possible underlying mechanisms.
Optimal treatment approach for intracranial germinoma: a systematic review and meta-analysis.
BMC Cancer
January 2025
National Center for Neurological Disorders, Shanghai, 200052, China.
Background: To determine the optimal treatment modality for intracranial germinoma (IG).
Materials And Methods: A search of Medline, Embase, Web of Science and Cochrane Library was conducted up to April, 2024. Pooled risk ratio (RR) and 95% confidence interval (CI) were calculated.
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