Who benefits from lipid-screening programmes?

Br J Hosp Med

Published: December 1992

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Article Synopsis
  • Familial Hypercholesterolemia (FH) is an inherited condition that heightens the risk of early cardiovascular disease, making early lifestyle changes and treatment critical.
  • Although effective treatments exist, FH remains underdiagnosed and not consistently treated, particularly in pediatric care.
  • A study analyzing parental experiences found that while there is strong support for universal lipid screening in children, many parents expressed concerns about the lack of follow-up care after diagnosis.
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Pediatric Lipid Screening Prevalence Using Nationwide Electronic Medical Records.

JAMA Netw Open

July 2024

Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.

Importance: Universal screening to identify unfavorable lipid levels is recommended for US children aged 9 to 11 years and adolescents aged 17 to 21 years (hereafter, young adults); however, screening benefits in these individuals have been questioned. Current use of lipid screening and prevalence of elevated lipid measurements among US youths is not well understood.

Objective: To investigate the prevalence of ambulatory pediatric lipid screening and elevated or abnormal lipid measurements among US screened youths by patient characteristic and test type.

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Overcoming the real and imagined barriers to cholesterol screening in pediatrics.

J Clin Lipidol

June 2024

Department of Genomic Health, Geisinger, Danville, PA, USA; Heart and Vascular Institute, Geisinger, Danville, PA, USA. Electronic address:

Recent guidance by the United States Preventive Services Task Force has renewed the debate surrounding the benefits of pediatric lipid screening. This commentary reviews the evolution of the pediatric lipid screening recommendations in the United States, followed by an exploration of real and imagined challenges that prevent optimal cholesterol screening rates in children. Real challenges substantively prevent the uptake of these guidelines into practice; imagined challenges, such as identifying the best age to screen, are often context-dependent and can also be surmounted.

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Importance: Lipid screening in childhood and adolescence can lead to early dyslipidemia diagnosis. The long-term benefits of lipid screening and subsequent treatment in this population are uncertain.

Objective: To review benefits and harms of screening and treatment of pediatric dyslipidemia due to familial hypercholesterolemia (FH) and multifactorial dyslipidemia.

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