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Profiles of travelers to intermediate-high health risk areas following the reopening of borders in the COVID-19 crisis: A clustering approach.
Travel Med Infect Dis
November 2023
International Vaccination Center at Santa Cruz de Tenerife, Spanish Ministry of Health, Spain; University of La Laguna, Research Center of Social Inequality and Governance (CEDESOG), Spain.
Background: The reactivation of international travel in 2021 has created a new scenario in which the profile of the traveler to medium-high health risk areas may well have changed. However, few studies have analyzed this new profile since the reopening of borders in that year.
Methods: We designed an ad hoc questionnaire that was administered face-to-face by our medical team during appointments with 330 travelers in the second half of 2021.
Interventions for men and women with their first episode of genital herpes.
Cochrane Database Syst Rev
August 2016
Department of Obstetrics and Gynaecology, University of Auckland, Private Bag 92019, Auckland, New Zealand, 1023.
Background: Genital herpes is incurable, and is caused by the herpes simplex virus (HSV). First-episode genital herpes is the first clinical presentation of herpes that a person experiences. Current treatment is based around viral suppression in order to decrease the length and severity of the episode.
View Article and Find Full Text PDFOn systems and control approaches to therapeutic gain.
BMC Cancer
April 2006
Department of Epidemiology and Biostatistics Case Western Reserve University, Cleveland, Ohio 44106, USA.
Background: Mathematical models of cancer relevant processes are being developed at an increasing rate. Conceptual frameworks are needed to support new treatment designs based on such models.
Methods: A modern control perspective is used to formulate two therapeutic gain strategies.
Is coulomb explosion a damaging mechanism for (125)IUdR?
Int J Radiat Biol
April 2005
Department for Safety and Radiation Protection, Forschungszentrum Jülich GmbH, D-52425 Jülich, Germany.
Purpose: To test the integrity of the thymine molecule that experiences an increasing number of charges due to the loss of Auger electrons emitted by the decay of incorporated 125I. Besides the radiation action of these electrons, Coulomb explosion is suspected to be an additional mechanism responsible for the strong radiotoxic effect of decaying DNA-incorporated 125I. The two-step decay process initiates a first Auger cascade within 10(-16) to 10(-14) s resulting in the release of about 7 electrons on average and a corresponding large positive charge on the 125Te daughter atom.
View Article and Find Full Text PDFHypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.
Acta Oncol
February 2002
Division of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam.
We describe our preliminary studies on the development of methods to measure hypoxia in standard paraffin sections of human tumors. Three parameters were investigated. First, image analysis of tumor vascularity yielded the parameter diffusion limited fraction (DLF), which is the amount of tumor tissue greater than a fixed distance from the nearest blood vessel.
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