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Hair cortisol of pigs in mixed organic farms: the influence of season, breeding system and sex.

Front Vet Sci

December 2024

Clinic for Ruminants and Pigs, Clinic for Reproduction and Large Animals, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.

Introduction: Measurement of hair cortisol concentration (HCC) is a useful tool for assessing the activity of the hypothalamic-pituitary-adrenal axis and thus evaluating the long-term adrenocortical response in different animal species and breeds. Robust indigenous pig breeds are highly adapted to the local environment and are preferred for organic farming, compared to the commercial breeds. We investigated whether seasonality, breeding system (indoor or outdoor) and sex influence HCC of pigs reared on organic farms.

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B2R-D2R Interaction in Prolactinomas and Nonfunctional Adenomas: Impact on Dopamine Resistance.

Endocrinology

October 2024

Laboratorio de Fisiopatología Hormonal, IBYME-CONICET, C1428ADN Buenos Aires, Argentina.

Prolactinomas, the most common pituitary-secreting adenomas, can be effectively treated with dopamine D2 receptor (D2R) agonists. However, a subset of them (∼20%) are resistant to dopamine-based therapies and require extirpation. The molecular mechanisms underlying their escape from dopaminergic regulation are not fully elucidated and may include alterations in D2R signaling.

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Article Synopsis
  • The review aimed to evaluate evidence from human studies on the link between radiofrequency electromagnetic fields (RF-EMF) exposure and the risk of certain cancers, especially focusing on brain and salivary gland tumors.
  • Researchers included various observational studies examining different types of RF-EMF exposure, such as from wireless phone use, environmental sources, and occupational settings, while emphasizing specific cancers in their analysis.
  • The study assessed the quality of each study using a risk-of-bias tool and utilized advanced statistical methods to synthesize results and determine confidence in the evidence gathered.
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Article Synopsis
  • * In a study with adult zebrafish, exposure to clomipramine led to increased time spent on the surface of a novel tank and reduced overall motor activity, indicating possible behavioral changes.
  • * Despite these behavioral changes, there were no significant differences in cortisol levels in the fish, suggesting that while clomipramine affects surface-dwelling and activity, it may not alter stress hormone levels in the short term.
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Purpose: The contents of Rathke's cleft cysts (RCCs) vary from clear and slightly viscous to purulent. Surgical treatment of symptomatic RCCs involves removing the cyst contents, whereas additional cyst-wall opening to prevent reaccumulation is at the surgeon's discretion. The macroscopic findings of the cyst content can reflect the nature of RCCs and would aid in surgical method selection.

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