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N-acetyl-tryptophan in Acute Kidney Injury after Cardiac Surgery.

J Am Soc Nephrol

January 2025

State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.

Background: Cardiac surgery-associated acute kidney injury is a common serious complication after cardiac surgery. Currently, there are no specific pharmacological therapies. Our understanding of its pathophysiology remains preliminary.

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Background: The application of international recommendations for paediatric maintenance haemodialysis (HD) could be strengthened by national laws or written recommendations. Our aim was therefore to describe the national rules governing paediatric maintenance HD in European countries.

Methods: A national representative, approved by the president of each paediatric nephrology society, was contacted in all 42 European countries to complete two online questionnaires.

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Congenital eyelid imbrication syndrome is rare and ranges from mild overriding of the upper eyelid on the lower eyelid to manually irreversible total upper eyelid eversion. The authors report two cases. One resolved with temporary tarsorraphies.

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Surveillance for variants escaping detection with the Aptima Combo 2 assay in Canada from 2019 to 2021.

Microbiol Spectr

January 2025

National Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Unlabelled: Nucleic acid amplification tests (NAATs) are the method of choice for diagnosis, but these strategies are susceptible to target site mutations. variants escaping detection with the Aptima Combo 2 (AC2) assay on the Hologic Panther instrument from 23S rRNA mutations have been reported in Nordic countries, England, Japan, and the United States. Given the potential for false negative results, this study investigated whether strains of with AC2 target site mutations were present in Canada.

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The Prevalence of Peripheral Erythrophagocytosis in Pediatric Immune-Mediated Hemolytic Anemia.

Hematol Rep

January 2025

Children's Haematology and Cancer Centre, Mount Elizabeth Hospital, Singapore 228510, Singapore.

Background: Peripheral erythrophagocytosis appears to be a unique sign of acquired immune-mediated hemolytic anemia. It is said to be rare but its prevalence among patients with autoimmune hemolytic anemia has not been studied.

Methods: In this retrospective study from July 2014 to June 2024, the clinical and laboratory features, treatment and outcomes of children diagnosed with autoimmune hemolytic anemia were described.

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