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Surveillance of Ancylostoma caninum in naturally infected dogs in Quebec, Canada, and assessment of benzimidazole anthelmintics reveal a variable efficacy with the presence of a resistant isolate in imported dogs.
Vet Parasitol Reg Stud Reports
July 2024
Research Group in Animal Pharmacology of Quebec (GREPAQ) - Université de Montréal, 3200 Sicotte St., Saint-Hyacinthe, QC J2S 2M2, Canada; Université de Montréal Hospital Research Center (CRCHUM), Montréal, QC H2X 0A9, Canada. Electronic address:
Ancylostoma caninum is a widely prevalent parasitic nematode in dogs across the world. There has been a notable increase in reports of anthelmintic resistance in A. caninum within the United States of America in recent years, which has led us to investigate the potential of this scenario in Canada.
View Article and Find Full Text PDFReflecting on the past and fast forwarding to present day anthelmintic resistant Ancylostoma caninum-A critical issue we neglected to forecast.
Int J Parasitol Drugs Drug Resist
August 2023
Veterinary Clinical Sciences, The Ohio State University, USA.
Reports of anthelmintic resistance in Ancylostoma caninum are increasing in frequency in the United States of America (USA). In the last few years in vitro and in vivo studies characterized individual isolates, demonstrating multiple anthelmintic drug resistance (MADR). In 2021, the American Association of Veterinary Parasitologists initiated a hookworm task force to address this issue.
View Article and Find Full Text PDFCompte rendu The canine hookworm A novel threat for anthelmintic resistance in Canada.
Can Vet J
April 2023
Faculté de médecine vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Nezami, Godoy); Hôpital vétérinaire de Buckingham, 606 Avenue de Buckingham, Gatineau, Québec J8L 2H5 (Blanchard).
The canine hookworm is one of the most prevalent parasitic nematodes in dogs worldwide and has the potential for zoonotic transmission to humans, including the development of cutaneous larva migrans. Recent confirmation of anthelmintic resistance (AR) in to several anthelmintic classes, mainly in the USA, indicates the potential for this scenario in Canada. We consider various factors that may lead to resistant isolates in Canada, such as the widespread use of antiparasitic drugs without the assessment of efficacy; increased prevalence in various Canadian provinces; and the importation of dogs, mostly from the USA, with a history of persistent infection by .
View Article and Find Full Text PDFComparative efficacy of ivermectin and fenbendazole against ancylostomiasis in dogs.
J Parasit Dis
March 2023
Department of Veterinary Clinical Medicine, College of Veterinary Science and Animal Husbandry, Odisha University of Agriculture and Technology, Bhubaneswar, 751003 India.
The present experiment was carried out to assess the comparative efficacy of ivermectin and fenbendazole individually for anthelmintic therapy for the hookworm infested dogs. Dogs presented to the Department of Veterinary Clinical Medicine or Veterinary Clinical Complex, Bhubaneswar were randomly screened for infection and the positive dogs were selected for the therapeutic trial Faecal samples were collected randomly from presented dogs immediately after defaecation or from the rectum directly using a faecal scoop. The collected sample was examined by floatation technique to detect the positive cases of infection.
View Article and Find Full Text PDFHighly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man.
Medicina (Kaunas)
August 2022
Department of Otorhinolaryngology and Maxillofacial Surgery, Military University Hospital, 16902 Prague, Czech Republic.
Sarcomas in the head and neck area are rare diseases with an incidence of under 1% of all head and neck malignant tumours. Osteosarcomas or osteogenic sarcomas consist of neoplastic cells that produce osteoid bone or immature bone. Sarcomas develop more in the mandible than the maxilla.
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