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Neonatal Nutrition and Brain Structure at 7 Years in Children Born Very Preterm.
JAMA Netw Open
January 2025
Liggins Institute, University of Auckland, Auckland, New Zealand.
Importance: Neonatal protein intake following very preterm birth has long lasting effects on brain development. However, it is uncertain whether these effects are associated with improved or impaired brain maturation.
Objective: To assess the association of neonatal protein intake following very preterm birth with brain structure at 7 years of age.
Efficacy and Safety Assessment of Antifungal Prophylaxis with Posaconazole Using Therapeutic Drug Monitoring in Pediatric Patients with Oncohematological Disorders-A Single-Centre Study.
J Fungi (Basel)
January 2025
Department of Pediatric Bone Marrow Transplantation, Oncology and Hematology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Introduction: Posaconazole is recommended for prophylaxis in pediatric immunocompromised patients. Due to its variability in bioavailability and drug-to-drug interactions, EBMT recommends regimens based on therapeutic drug monitoring (TDM).
Materials And Methods: In total, 171 oncohematological pediatric patients on posaconazole prophylaxis were included.
Comprehensive quantification of C4 to C26 free fatty acids using a supercritical fluid chromatography-mass spectrometry method in pharmaceutical-grade egg yolk powders intended for total parenteral nutrition use.
Anal Bioanal Chem
January 2025
Department of Chemistry - Biomedical Center, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden.
Free fatty acids (FFAs) are important energy sources and significant for energy transport in the body. They also play a crucial role in cellular oxidative stress responses, following cell membrane depolarization, making accurate quantification of FFAs essential. This study presents a novel supercritical fluid chromatography-mass spectrometry (SFC-MS) method using selected ion recording in negative electrospray ionization mode, enabling rapid quantification of 31 FFAs within 6 min without derivatization.
View Article and Find Full Text PDFNutritional support in children treated for advanced adrenocortical carcinoma.
Pediatr Surg Int
January 2025
Department of Surgery, St. Jude Children's Research Hospital, MS 133, 262 Danny Thomas Place, Memphis, TN, 38105, USA.
Purpose: Adrenocortical carcinoma (ACC) is a rare, aggressive pediatric malignancy. Advanced ACC requires multimodal treatment, including surgery and systemic chemotherapy including cisplatin, etoposide, doxorubicin, and mitotane. This is associated with significant gastrointestinal toxicity, resulting in many patients being unable to complete scheduled therapy.
View Article and Find Full Text PDFValidation the modified subjective global nutrition assessment (mSGNA) for assessing malnutrition among hospitalized children.
Early Hum Dev
January 2025
Viet Nam National Children's Hospital, 18/879 La Thanh, Dong Da, Hanoi 100000, Viet Nam.
Objectives: To validate a modified Subjective Global Nutritional Assessment (mSGNA) for assessing nutritional status among Vietnamese children.
Study Design: A cross-sectional study was conducted at the National Children's Hospital in Vietnam, where 200 children were assessed using mSGNA, Subjective Global Nutritional Assessment (SGNA), and a standardized method developed by the Academy of Nutrition and Dietetics (AND) and the American Society for Parenteral and Enteral Nutrition (ASPEN).
Results: The mSGNA showed high accuracy with 82.
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